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TP53 BRCA1 CRISPR single-cell cancer

Speleman(Frank),Park(Julie R),Henderson(Ta... Am Soc Clin Oncol Educ Book 0000-00-00

...MYCN was discovered in the early 1980s, our understanding of neuroblastoma oncogenesis has advanced in the last decade a...

Suzuki(Kazuhito),Yamamoto(Kouhei),Arakawa(... Anticancer Drugs 0000-00-00

...MYCN were not by quantitative real-time reverse-transcription-PCR. Incubation with I-BET151 induced downregulation of MY...

Lodrini(Marco),Poschmann(Gereon),Schmidt(V... J Proteome Res 0000-00-00

MYCN and HDAC2 jointly repress the transcription of tumor suppressive miR-183 in neuroblastoma. Enforced miR-183 express...

Craig(Brian T),Rellinger(Eric J),Alvarez(A... Biochem Biophys Res Commun 0000-00-00

...MYCN-amplified neuroblastoma cell lines form spheres more frequently than non-MYCN-amplified cell lines. We also show th...

Mitchell(Camilla B),O'Neill(Geraldine M) Cell Adh Migr 0000-00-00

...MYCN amplification is associated with universally poor prognosis, the clinical course of patients whose tumors lack MYCN...

Zins(Karin),Schäfer(Romana),Paulus(Patrick... Oncotarget 0000-00-00

...MYCN-single copy SK-N-AS and MYCN-amplified SK-N-DZ high-risk NB cells. We demonstrate that stimulation of FZD2 by Wnt3a...

Ma(Youngeun),Lee(Ji Won),Park(Soo Jin),Yi(... J Korean Med Sci 0000-00-00

...MYCN is a well-known poor prognostic factor in NB patients. As the MYCN amplification status is usually tested using tum...

Marrano(Paula),Irwin(Meredith S),Thorner(P... Genes Chromosomes Cancer 0000-00-00

...MYCN-amplified neuroblastoma to determine MYCN copy number in the primary tumor, pre- and post-treatment, and in metasta...

Casey(Dana L),Kushner(Brian H),Cheung(Nai-... Int J Radiat Oncol Biol Phy... 0000-00-00

...MYCN-amplified tumors or serum lactate dehydrogenase ≥1500 U/L (P=.09 and P=.06, respectively).,After intensive chemothe...

Guan(J),Tucker(E R),Wan(H),Chand(D),Daniel... Dis Model Mech 0000-00-00

...MYCN Taken together, our results suggest PF-06463922 is a potent inhibitor of crizotinib-resistant ALK mutations, and hi...

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