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A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell ...

Allen(John D),Jackson(Sonja C),Schinkel(Al... Cancer Res 2002-05-31

...Bcrp1 exclusively at R482. Although the mouse Bcrp1 amino acid substitutions (M or S) are distinct from those seen in th...

Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, functio...

Uchida(Naoyuki),Leung(Frank Y K),Eaves(Con... Exp Hematol 2002-09-16

...Bcrp1 and mdr-1a/b) and the related abilities to efflux Hoechst 33342 (Hst) and Rhodamine-123 (Rho) are features of prim...

Bcrp1 gene expression is required for normal numbers of side population stem ...

Zhou(Sheng),Morris(John J),Barnes(Yuxiao),... Proc Natl Acad Sci U S A 2002-10-28

...Bcrp1 in the SP phenotype. To define the relative role of these transporters, we generated Bcrp1 null mice and evaluated...

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells ...

Zhou(S),Schuetz(J D),Bunting(K D),Colapiet... Nat Med 2001-10-18

...Bcrp1 (also known as Abcg2 murine/ABCG2 human) gene is a conserved feature of stem cells from a wide variety of sources....

Role of breast cancer resistance protein in the bioavailability and fetal pen...

Jonker(J W),Smit(J W),Brinkhuis(R F),Malie... J Natl Cancer Inst 2000-11-09

...Bcrp1, the murine homologue of BCRP, was expressed in the polarized mammalian cell lines LLC-PK1 and MDCK-II, and the di...

The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines...

Allen(J D),Brinkhuis(R F),Wijnholds(J),Sch... Cancer Res 1999-09-30

...Bcrp1, the mouse homologue of the human ATP-binding cassette transporter gene BCRP/MXR/ABCP, and greatly elevated expres...

P-Glycoprotein, not BCRP, Limits the Brain Uptake of [(18)F]Mefway in Rodent ...

Choi(Jae Yong),Song(Jin Sook),Lee(Minkyung... Mol Imaging Biol 0000-00-00

...Bcrp1((-/-))) was comparable to that of the double knockout mice (dKO, Mdr1a/b((-/-))) and 2-fold those of the wild-type...

A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at th...

Kim(Do-Geun),Bynoe(Margaret S) J Clin Invest 0000-00-00

...BCRP1, an efflux transporter that is highly expressed in the CNS vasculature and other tissues. Finally, we determined t...

Methods to Discover Alternative Promoter Usage and Transcriptional Regulation...

Natarajan(Karthika),Xie(Yi),Nakanishi(Take... J Vis Exp 0000-00-00

...Bcrp1 (Abcg2), the murine orthologue of the ABC transporter Breast Cancer Resistance Protein (BCRP, ABCG2), has at least...

Simultaneous Prediction of four ATP-binding Cassette Transporters' Substrates...

Aniceto(Natália),Freitas(Alex A),Bender(An... Mol Inform 0000-00-00

...BCRP1, P-gp/MDR1 and MRP1 and MRP2, using a dataset of 1493 compounds. To this end, two multi-label classification QSAR ...

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