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Nakanishi(Yoshito),Walter(Kimberly),Spoerk... Cancer Res 2016-07-29

...PDK1 at the membrane and driving PI3K signaling to a level that could withstand treatment with proximal inhibitors. Fina...

Battello(Nadia),Zimmer(Andreas David),Goeb... Cancer Metab 2016-02-18

...PDK1 can induce hypoxia-like metabolic changes, although to a lesser extent than hypoxia itself. Since PDK1 is overexpre...

Park(Hana),Jeoung(Nam Ho) Biochem Biophys Res Commun 2016-05-27

...PDK1 - 3) remained unchanged. Additionally, we observed that LPS treatment induced phosphorylation of Jun N-Terminal Kin...

Izutani(Yasuyuki),Yogosawa(Shingo),Sowa(Yo... Int J Oncol 2016-06-09

...PDK1 is incorrect in the published paper. The corrected version of Fig. 5B is shown below. Also in Fig. 6B, the DMSO-tre...

Pastor-Flores(Daniel),Schulze(Jörg O),Bahí... Biochim Biophys Acta 2016-06-07

Pkh is the yeast ortholog of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1). Pkh phosphorylates the ...

Bueno-Silva(Bruno),Kawamoto(Dione),Ando-Su... PLoS One 2016-07-06

...Pdk1, Pak1, Nfkb1, Mtcp1, Gsk3b, Fos and Elk1) and of Il1β and Il1f9 (fold-change rate > 5), which were further confirme...

Li(Qingjie),Winston(John H),Sarna(Sushil K... Am J Physiol Regul Integr C... 2016-06-09

...PDK1), pAKT(Ser473), and phosphorylated 4E-binding protein (p4E-BP1)(Thr70), suggesting AKT activation and enhanced NGF ...

Xie(Lin),Tang(Qiongyan),Yang(Ling),Chen(Li... Mol Cell Endocrinol 2016-10-06

...PDK1) and Akt also dramatically abolished IGF-I-induced egfr expression, suggesting that the classical PI3K/Akt pathway ...

Park(Hyojin),Lee(Sungwoon),Shrestha(Praves... J Cell Biol 2016-02-12

...PDK1 pleckstrin homology domain. A synthetic peptide containing the AMIGO2 465-474 residues abrogated the AMIGO2-PDK1 in...

Vieira(Gabriella Cunha),Chockalingam(S),Me... Oncotarget 2016-09-20

...PDK1-independent mechanism. LGR5 expression is cell cycle regulated and LGR5 depletion triggers G1 cell-cycle arrest, in...