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An Update on Circumventing Multidrug Resistance in Cancer by Targeting P-Glycop…

Yang(X),Li(X),Duan(Z),Wang(X) Curr Cancer Drug Targets 2018-00-00

...Pgp), which decreases the intracellular accumulation of chemotherapeutic agents in drug-resistant cancer cells. Thus, Pg...

Biocompatible nanogels with tunable size and tailorable properties: A simple sy…

Li(H),Zeng(S),Zhou(L) Int J Biol Macromol 2025-05-00

...PGP-based NGs (PGP-NGs) by leveraging the self-assembly and disulfide crosslinking techniques, without using any surfact...

Role of P-glycoprotein in deoxynivalenol-mediated in vitro toxicity.

Ivanova(L),Fæste(CK),Solhaug(A) Toxicol Lett 2018-03-01

...Pgp) in the apical enterocyte membrane. Interaction with Pgp was studied in human colorectal adenocarcinoma (Caco-2) cel...

Intracellular Doppler Spectroscopy detects altered drug response in SKOV3 tumor…

Narayanan(G),Merrill(D),An(R),Nolte(DD),Ture… Biochem Biophys Res Commun 2019-00-05

...Pgp-silenced cell line (SKOV3cis-sh). A specific Pgp inhibitor, zosuquidar, was used to study the effects of Pgp inhibit...

Modulation of the multidrug resistance P-glycoprotein: detection with technetiu…

Luker(GD),Fracasso(PM),Dobkin(J),Piwnica-Wor… J Nucl Med 1997-03-00

...Pgp) has been documented in nearly all forms of human cancers and increased levels of Pgp in some tumors correlate with ...

Co-translational effects of temperature on membrane insertion and orientation o…

Zhang(JT),Chong(CH) Mol Cell Biochem 1996-06-07

...pgp 1 Pgp is expressed in more than one topological form and that the generation of these structures is modulated by cha...

Synthesis and evaluation of dihydropyrroloquinolines that selectively antagoniz…

Lee(Brian D),Li(Zhanjiang),French(Kevin J),Z… J Med Chem 2004-04-23

...PGP-4008 was the most effective at inhibiting Pgp in vitro and was further evaluated in vivo. PGP-4008 inhibited tumor g...

Interaction of antiepileptic drugs with human P-glycoprotein in vitro.

Weiss(Johanna),Kerpen(Christian Johannes),Li… J Pharmacol Exp Ther 2003-10-23

...Pgp. Indeed, several AEDs are substrates and to some extent also inducers of Pgp. To date nothing is known about possibl...

Evidence that the Pgp-1 glycoprotein is expressed on thymus-homing progenitor c…

Lesley(J),Hyman(R),Schulte(R) Cell Immunol 1985-04-01

...Pgp-1 glycoprotein. One hypothesis is that some or all of these Pgp-1+ thymocytes represent thymocyte progenitors or the...

Phosphorylated Crkl reduction levels are associated with the lowest P-glycoprot…

Vasconcelos(Flavia Cunha),Nestal de Moraes(G… Leuk Res 2014-02-18

...Pgp activity levels compared with patients exhibiting higher Pgp activity levels (p=0.0045). Pgp activity in association...

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