Johnson(Timothy E),Zhang(Xiaohua),Shi(Shu)... Toxicol Appl Pharmacol 2005-12-30

...rap1a. Interestingly, Compound A and Compound B had differential effects on ATP levels. Taken together, these observatio...

Segawa(Hidekazu),Kimura(Shinya),Kuroda(Jun... Br J Haematol 2005-09-22

...Rap1A in leukaemic cells in vitro and synergised with imatinib to enhance the survival of mice engrafted with cells from...

Han(Hyunsil),Stessin(Alexander),Roberts(Ju... J Exp Med 2005-09-29

...Rap1A, a phox-associated guanosine triphosphatase that is regulated by cAMP. Thus, TNF turns on phox through a Ca2+-trig...

Vielkind(Susina),Gallagher-Gambarelli(Maig... J Immunol 2005-08-31

...Rap1A in vivo. The regulated activity of integrins is needed for cell motility and in the present study it was seen that...

Tilley(Douglas G),Maurice(Donald H) Mol Pharmacol 2005-10-27

...Rap1A cAMP-dependent signaling cascade plays no role in regulating PDE4D expression in either VSMC phenotype. Our data a...

Leusen(J H),Verhoeven(A J),Roos(D) Front Biosci 2004-11-24

...Rap1A, and 2. there are multiple signal transduction pathways leading to activation of the NADPH oxidase. The most likel...

Yang(Bo),Gao(Xiao-Kang),Wang(He),Liu(He-Li... Zhonghua Nan Ke Xue 2004-02-17

...RAP1A was analyzed by bibliogrphic retrieval.,Six hundred and twenty-three differential expressed genes were found, amon...

Keiper(Melanie),Stope(Matthias B),Szatkows... J Biol Chem 2004-12-28

...Rap1A. The receptor actions were independent of protein kinase A but fully mimicked by an Epac-specific cAMP analog as w...

Arthur(William T),Quilliam(Lawrence A),Coo... J Cell Biol 2004-11-22

...Rap1a activates Rac1 and requires Rac1 to enhance spreading, whereas Rac1 induces spreading independently of Rap1. Activ...

Johnson(Timothy E),Zhang(Xiaohua),Bleicher... Toxicol Appl Pharmacol 2004-12-21

...rap1a, a geranylgeranylated protein, was inhibited by Compound A in myotubes at concentrations that induced apoptosis. A...