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YAP-mediated mechanotransduction promotes hepatocellular carcinoma progression …

Zhang(MN),Wen(XP),Liu(JY),Xiong(Y),Miyagishi… Acta Pharmacol Sin 2026-09-01

...TEAD4) mechano-responsive transcription factor complex, whose increased expression in stiff matrix promotes tumor cell p...

YAP/TEAD4/SP1-induced VISTA expression as a tumor cell-intrinsic mechanism of i…

Zhu(Z),Ding(R),Yu(W),Liu(Y),Zhou(Z),Liu(CY) Cell Death Differ 2025-05-00

...TEAD4. As a result, SP1 enhanced the transcriptional activity of YAP/TEAD and coregulated the expression of a group of Y...

Mechanisms of trophectoderm fate specification in preimplantation mouse develop…

Sasaki(H) Dev Growth Differ 2010-04-00

...Tead4 and Cdx2. The transcriptional activity of Tead4 is regulated by the position-dependent Hippo signaling pathway, th...

VGLL4 modulates Paneth cells and sustains intestinal homeostasis.

Zhang(H),Wang(Z),Wang(X),Yu(W),Zhang(G),Zhan… EMBO Rep 2026-03-00

...TEAD4 and ATOH1, stimulating GFI1 expression and promoting Paneth cell differentiation. Furthermore, VGLL4 forms a compl...

YAP1 induces invadopodia formation by transcriptionally activating TIAM1 throug…

Shen(J),Huang(Q),Jia(W),Feng(S),Liu(L),Li(X)… Oncogene 2022-00-00

...TEAD4 complex. Our results demonstrate that YAP1 could promote TEAD4 binding to the enhancer region of TIAM1, which acti...

TEAD4 modulated LncRNA MNX1-AS1 contributes to gastric cancer progression partl…

Shuai(Y),Ma(Z),Liu(W),Yu(T),Yan(C),Jiang(H),… Mol Cancer 2020-00-10

...TEAD4-involved upstream regulatory mechanism of MNX1-AS1 was explored through ChIP and luciferase reporter assays. The m...

VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specificatio…

Yang(Y),Jia(W),Luo(Z),Li(Y),Liu(H),Fu(L),Li(… Nat Commun 2024-01-17

...TEAD4 (TEA domain transcription factor 4) to regulate chromatin accessibility at target gene loci through histone acetyl...

RAD21 amplification epigenetically suppresses interferon signaling to promote i…

Deng(P),Wang(Z),Chen(J),Liu(S),Yao(X),Liu(S)… J Clin Invest 2022-00-15

...TEAD4 transcriptional corepressors and recruits the NuRD complex to suppress interferon (IFN) signaling. In multiple cli...

The Role of BDNF, YBX1, CENPF, ZSCAN4, TEAD4, GLIS1 and USF1 in the Activation …

Liu(B),Yan(J),Li(J),Xia(W) Int J Mol Sci 2023-11-07

...TEAD4, GLIS1, and USF1 genes can lead to embryonic development failure. This article reviews the results of studies on t...

Targeting IRF3 as a YAP agonist therapy against gastric cancer.

Jiao(S),Guan(J),Chen(M),Wang(W),Li(C),Wang(Y… J Exp Med 2018-00-05

...TEAD4 in the nucleus to enhance their interaction, promoting nuclear translocation and activation of YAP. IRF3 and YAP-T...

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