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Targeting phosphodiesterase 10A disrupts MAPK signaling pathways in the tumor...

Gazi(MY),Ye(Y),Okoko(OD),Wang(X),Simon(SE)... bioRxiv 2026-02-28

...Batf3-expressing DCs to elicit antitumor CD8 + T cell response, and its synergy with anti-PD-1 therapy. Comprehensive im...

Tim-3-targeted vaccines overcome tumor immunosuppression and reduce cDC1 depe...

Fu(C),Ma(T),Clausen(BE),Mellman(I),Jiang(A... Proc Natl Acad Sci U S A 2026-03-24

...Batf3-/- mice lacking cDC1s, anti-Tim-3-based vaccines still elicited significant CD8 T cell cross-priming and tumor con...

The CARM1 epigenetic enzyme inhibits cross-presenting dendritic cell function...

Zhang(X),Xirenayi(S),Zhao(Y),Wang(W),Han(Y... Science 2026-07-09

...BATF3-Jun and RelA sites that are critical for cDC1 function and activation. Transforming growth factor-β regulated Carm...

Real-world insights into genomic reprogramming during CAR-T cell manufacturin...

Das(N),Mehta(P),Gupta(K),Katharia(R),Pabbi... Front Immunol 2026-00-00

...BATF3, LIF) in final product as compared to leukapheresis sample. Concurrent downregulation of innate immune and myeloid...

IL10R Inhibition Induces Neutrophil Tumoricidal Activity.

Khalil(DN),Gomez(R),Regev(A),Samaan(F),Mar... Cancer Immunol Res 2026-05-04

...Batf3-dependent pathway in which IL12 and IFNγ secretion results in oncolytic neutrophil activity. Using a combination o...

LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitu...

Chakraborty(AK),Kroehling(L),Raut(RD),Chou... Cancer Res 2026-01-16

...BATF3 and CXCL9), T-cell markers (CXCR3), and MHC-I (HLA-A). Overall, LSD1 inhibition in tumor cells upregulates MHC-I e...

Intraperitoneal administration of cationic liposomes containing a TLR3 agonis...

Schmidt(ST),Zimmermann(J),Wørzner(K),Perri... Vaccine 2026-01-05

...BATF3-dependent conventional type I dendritic cells (cDC1) displaying a migratory cDC1 phenotype (CD11c+XCR1+CD103+). Ge...

Identification of biomarkers between coronary artery disease and non-alcoholi...

Lin(Y),Song(J),Li(X) Front Genet 2025-00-00

...BATF3, SOCS2, and GPER, all with ROC values above 0.7, validated in external datasets. GSEA revealed that these genes ac...

Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendrit...

Ascic(E),Fontanari(G),Thrasyvoulou(M),Pére... J Vis Exp 2025-08-01

...BATF3 (collectively referred to as PIB)-in cancer cells, followed by subcutaneous implantation of a mixture of transduce...

Deciphering transcriptomic signatures in schizophrenia, bipolar disorder, and...

Priyanka,Kumar(R),Kumar(V),Kumar(A),Rana(S... Front Psychiatry 2025-00-00

...BATF3, IRF and NFKB1; while SCZ demonstrated unique regulation through ATF5, CREB3L3, SNAI1, NFIL3, CEBPB, RELB and IRF ...

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