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Fermented Clostridium butyricum GKB7 Inhibits Osteoarthritis Induced by Anter...

Chen(WC),Chen(LC),Tsai(YS),Chen(YP),Chen(Y... Int J Med Sci None

...COL2A1. Bone loss and cartilage degradation were blocked as a result of this activity. According to our findings, fermen...

ZDHHC14 Attenuates Osteoarthritis Progression through Metabolic Pathways: Mul...

Di(J),Guo(Z),Chen(T),He(J),Qin(Y),Wang(F),... Exp Gerontol 2026-06-01

...COL2A1 and SOX9 decreased, and the expression of ADAMTS5 and MMP13 increased. Functional experiments demonstrated ZDHHC1...

CH25H-mediated cholesterol metabolism drives chondrogenic differentiation in ...

Wang(Y),Ye(W),Chen(Y),Zhuang(Y),Qin(Z),Luo... Commun Biol 2026-04-13

...COL2A1. In ADSCs, FPR1 knockdown and rescue experiments, together with pharmacological inhibition of FPR1 or AKT, suppor...

The m5C demethylase TET1 is identified as a key regulator of scleral remodeli...

Jia(S),Yang(L),Wei(P),Yu(J),Han(G),Wang(Y) Clin Epigenetics 2026-03-09

...Col2a1 (p = 0.002) and Fbn1 (p < 0.001). Our study reveals substantial alterations in TET1 expression and m5C modificati...

Role of WIF-1 in regulating chondrocyte dedifferentiation and matrix producti...

Chu(YY),Asawa(Y),Tsuji(N),Sakamoto(T),Liu(... Regen Ther 2026-03-00

...COL2A1, and WIF1 were evaluated by immunohistochemistry. Late-passage HACs showed marked dedifferentiation, including re...

Development of biodegradable methacrylated guar gum 3D bioprinting bioinks fo...

Shang(Y),Jiang(Q),Yang(Y),Xi(L),Li(J),Shen... J Mater Sci Mater Med 2026-03-11

...COL2A1), Aggrecan (ACAN), and SRY-box transcription factor 9 (SOX9). The novel 3D bioprinting GG-MA hydrogel scaffolds d...

Avenanthramide C and chondroitin sulphate promote chondrogenic differentiatio...

Sun(P),Lim(W),Talchai(SC),Khemarangsan(V) Sci Rep 2026-03-11

...COL2A1 protein deposition, the primary collagen type that is cartilage tissue-specific. Co-administration of chondroitin...

Artificial mitochondria ameliorates osteoarthritis through restoring cellular...

Yan(W),Chen(Y),Wu(H),Gao(Z),Hu(X),Ao(Y),Ma... Bioact Mater 2026-07-00

...COL2A1, ACAN, SOX9) and suppressed inflammatory pathways (MMP3, IL6), while enhancing extracellular matrix biosynthesis....

Microenvironment-directed chondrogenesis of adipose-derived mesenchymal stem ...

Han(Y),Ma(H),Chen(J),Cheng(L),Li(K),Zhang(... Cell Tissue Bank 2026-03-13

...COL2A1, and ACAN. Meniscal implants instead displayed a fibrocartilage-like profile with robust COL I and tenomodulin ex...

Screening of an FDA-approved drug library reveals MEK1/2 inhibitors block pro...

Coryell(PR),Fernandez Davila(JG),Yanke(AB)... Osteoarthritis Cartilage 2026-06-00

...COL2A1 and ACAN expression and decreased levels of MMP-13 and IL-6 in chondrocytes isolated from OA patients. Trametinib...

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