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ENO1 as a Central Regulator Linking Metabolic Reprogramming to Tumor Plasticity.

Lin(TC) Int J Mol Sci 2026-05-16

...ENO1 across multiple cancer types. We first outline the physiological characteristics of ENO1 and its distribution in no...

Targeting the NAT1-ENO1-Lactate Axis Destabilizes PD-L1 to Reinvigorate Antit...

Liu(YX),Wu(WX),Zang(Y),Hu(G),Guo(X),Wang(Y... MedComm (2020) 2026-08-00

...ENO1), a key glycolytic enzyme, acetylating it at lysine 343 (K343) and thereby inhibiting its activity. However, loss o...

GUDCA drives colorectal cancer progression via ALKBH5-mediated m6A modificati...

Lin(R),Jin(S),Yang(W),Zhang(J),Jiang(J),Xi... Front Pharmacol None

...ENO1 mRNA and enhancing its translation efficiency. ALKBH5 deficiency drove glycolytic reprogramming and mTORC1 activati...

Histone Lactylation Mediated by circRNA-Facilitated FXR1 Phase Separation Pro...

Jiang(T),Liu(J),Hu(Q),Qi(J),Liu(B),Ma(N),X... Cancer Res 2026-08-05

...ENO1 mRNAs by enhancing the recognition of their m6A modification sites. Consequently, elevated PGK1 and ENO1 led to inc...

TGFβ Blockade by Inhibition of Enolase-1-Mediated Plasmin Targets Tumor-Assoc...

Chen(ML),Chung(IC),Huang(KC),Chao(KSC),Yua... Oncol Res None

...ENO1 monoclonal antibody. Methods: ENO1 expression and clinical relevance were evaluated in PDAC tissues by immunohistoc...

MBP1 inhibits AML proliferation through downregulating noncanonical Wnt/Ca2+ ...

Gao(B),Yan(W),Xue(J),Zhang(S),Wang(F),Kang... Leuk Lymphoma 2026-07-00

...ENO1 upregulation in primary AML patient samples compared to healthy donors, establishing an imbalanced ENO1/MBP1 ratio....

A Lamp2a-linked RNA secreted by ADSCs prevents ENO1-lactylation-glycolysis fe...

Cheng(S),Xia(B),Li(L),Zhao(S),Zhang(Q),Hui... Cell Death Dis 2026-03-02

...ENO1 levels in various BC datasets and revealed ENO1 protein lactylation in BC samples through 4D label-free lactylation...

Apoptosis-related gene model predicts the prognosis in patients with acute my...

Pei(X),Liu(W),Li(Y),Wei(H),Wang(M),Wang(J) Blood Sci 2026-06-00

...ENO1, SOD1, and SLC7A11) and constructed a 5-ARG prognostic model. Using this model, we successfully stratified patients...

Targeting the lactate-lactylation-glucose uptake axis: Cryptotanshinone repro...

Ni(X),Wang(C),Zhang(K),Zhang(M),Guo(J),Fan... Phytomedicine 2026-07-25

...ENO1 interaction. In vitro and in vivo models, including cell lines, xenografts, and patient-derived organoids, were emp...

Peripheral blood CD14 + monocytes in luminal breast carcinoma subtypes: in pr...

Alexovič(M),Bober(P),Marcin(M),Parnica(J),... Sci Rep 2026-02-10

...ENO1, KRT1, and AIDB were among the top 10 hits in LumA, LumB-HER2 − and LumB-HER2+, respectively, and can also likely b...

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