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Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, pla...

Ogbogu(PU),Roufosse(F),Akuthota(P),Kuna(P)... Nat Med 2026-06-00

...FIP1L1::PDGFRA-negative HES. The primary endpoint was time to first HES flare. In total, 133 patients (median (range) ag...

Comparison of gene fusion detection algorithms reveals frequently overlooked ...

Tamura(Z),Saito(Y),Kogure(Y),Oshikawa-Kuma... NPJ Precis Oncol 2026-04-04

...FIP1L1::PDGFRA), lowly expressed fusions, and IGH fusions (DUX4::IGH and IGH::NSD2). Targeted RNA-seq more sensitively d...

Persistent Hemorrhagic Lip Crusts as the Presenting Sign of Pediatric FIP1L1-...

Chiang(YK),Ho(YH) Pediatr Dermatol 2026-04-21

FIP1-like-1-platelet-derived growth factor receptor-α (FIP1L1-PDGFRA)-positive hypereosinophilic syndrome (HES) is a rar...

Novel LUC7L::NUTM1 fusion in PDGFRA-rearranged myeloproliferative neoplasm wi...

Zhou(J),Yao(H),Ren(J),Sun(K),Chen(D),Zhang... World J Surg Oncol 2026-03-12

...FIP1L1::PDGFRA fusion gene. The patient achieved stable disease imatinib (100 mg/day) treatment. This first report of du...

Organ Involvement and Constitutional Symptoms in Idiopathic Hypereosinophilic...

Łacwik(P),Kupryś-Lipińska(I),Kucharczyk(A)... J Clin Med 2026-07-16

...FIP1L1-PDGFRA RT-PCR and aberrant T-cell phenotyping on flow cytometry; secondary causes were excluded clinically. Each ...

Hypereosinophilic syndrome and suspected myeloid neoplasia in relapsed Hodgki...

Ibrahim(RAE),Ahmed(BA),Bahr(AR),ElShazly(M... Leuk Lymphoma 2026-08-30

...FIP1L1-PDGFRA rearrangement in 2% of cells. The patient required hospitalization for dehydration, renal dysfunction, and...

Harnessing AACR Project GENIE to Define the Molecular Features of Desmoplasti...

Kolluru(S),Horio(N),Torbenson(E),Hsia(B),T... Curr Issues Mol Biol 2026-01-15

...FIP1L1 and NRIP1. Our data highlights mutational variation across demographic cohorts. These patterns are vital to futur...

Loeffler Syndrome in FIP1L1-PDGFRA-Positive Myeloid Neoplasm.

Alcalá Ramírez Del Puerto(M),Sánchez Sánch... JACC Case Rep 2026-02-04

...FIP1L1-platelet-derived growth factor receptor α-positive myeloid/lymphoid neoplasm. Treatment with corticosteroids and ...

First-in-Class Dual PDGFR/Carbonic Anhydrase IX/XII Inhibitors: 6,7-Dimethoxy...

Roshdy(E),Řezníčková(E),Elbadawi(MM),Celik... J Med Chem 2026-02-12

...FIP1L1-PDGFRA-driven EOL-1 cells (GI50 = 2 nM), comparable to clinical agents. Mechanistic analyses revealed that 9d eff...

Genetic mapping of lifespan and mitochondrialstress response in C. elegans.

Auwerx(J),Li(X),Li(W),Gao(A),Zhu(Y),Katsyu... Res Sq 2025-07-31

...FIP1L1, which was functionally validated in C. elegans and humans. In the human UK Biobank, FIP1L1 was associated with m...

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