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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 t...

Jin(L),Zhang(J),Wang(W),Zhang(N),Liu(Y),Ti... Mol Med Rep 2026-07-00

...FOSL2) activated DYNC1H1 transcription by binding to enhancer regions. Functional validation established that the FOSL2/...

Hypoxia-Driven Mechanisms in Ischemic Heart Failure: A Bioinformatics, Machin...

Han(Q),Fan(R),Ma(J),Yuan(H),Guo(Y),Xue(Y),... Cardiovasc Toxicol 2026-08-26

...FOSL2, and PIM1. The SHAP analysis was instrumental in interpreting the predictive outcomes of the optimal model, the Ra...

FOSL2 Regulates PANoptosis in Cardiomyocytes and Heart Failure Progression Af...

Gu(R),Sun(Y) J Cardiovasc Transl Res 2026-07-28

...FOSL2 were upregulated in myocardial tissues of AMI-induced mice and hypoxia-exposed mouse cardiomyocytes. FOSL2 activat...

Fosl2/c-Jun dimer induces oxidative stress and endoplasmic reticulum stress b...

Zhang(Q),Jin(J),Wang(J) Biochim Biophys Acta Gen Su... 2026-07-29

...Fosl2, c-Jun, and Lcn2 were highly expressed in mouse and cell models of ICI. Fosl2 interacted with c-Jun, and the Fosl2...

Single-cell spatial transcriptomics reveals rewiring of RPE and Müller glia s...

Guo(H),Wei(L),Chen(B),Huang(J),Zhu(M),Li(X... Neurobiol Dis 2026-08-08

...Fosl2, and Junb, with predicted targets Osmr, A2m, and Stat3. Cell-cell communication analyses indicated coordinated cha...

Identification and Experimental Validation of Key Biomarkers for Rheumatoid A...

Han(Y),Wang(P),Wang(Y),Chen(G),Lan(M),Teng... J Inflamm Res None

...FOSL2, JUN, and EGR1 in the synovial tissue. This study identifies FOSL2, JUN, and EGR1 as potential markers for RA, sup...

PhiKan 083 Inhibits MYCN Expression in Liver Cancer Cells Independent of p53 ...

Xu(Y),Mishra(H),Takahashi(M),Nishimura(H),... ACS Pharmacol Transl Sci 2026-08-14

...FOSL2 showed a negative correlation. These findings suggest that PK83 suppresses MYCN expression and preferentially affe...

Multi-omics integration identifies VIM and LGALS3 as apoptosis-associated gen...

Wang(B),Wang(Y),Cao(W),Wang(P),Yang(X),Wan... Neuroscience 2026-08-19

...FOSL2, and MAFF showed higher regulon activity in TBI-reactive astrocytes, and there in silico knockout shifted reactive...

Spatial Transcriptomics of Human Decidua Identifies Molecular Signatures in R...

Sha(Q),Yu(Q),Chen(K),Wang(J),Wang(F),Jiang... Genomics Proteomics Bioinfo... 2026-03-27

...FOSL2 as a pivotal regulator orchestrating the spatial transformation of dNK1 cells. Decreased FOSL2 expression correlat...

FOSL2 Regulates PD-L1 and Modulates Hormone Therapy Response Heterogeneity.

Sun(F),Wang(B),Mei(S),Zhang(L),Wang(X),Liu... Mol Cancer Res 2026-05-04

...FOSL2 and PD-L1. Mechanistically, FOSL2 directly bound to the PD-L1 promoter to transcriptionally upregulate PD-L1, ther...

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