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Identification of Critical Genes for Recurrent Aphthous Ulcer by Transcriptome …

Fu(X),Zhang(H),Li(Y),Li(A),Liu(Q),Zeng(X) Oral Health Prev Dent 2026-09-09

...HCK, MICB, and SLC2A3 showed protective associations with RAU risk, whereas CD177 and IFITM1 were positively associated ...

Synthetic Substrate Discovery for Hck Kinase via Phage Display.

Kannan(A),Heier(JL),Motwani(DP),Meyers(HJ),A… Biochemistry 2026-07-07

...Hck kinase, followed by analysis of positional and motif enrichment to guide iterative substrate design. The novel subst...

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia.

Ren(L),Zhang(H),Bobileva(O),Nai(F),Bi(H),Cha… Blood 2026-06-18

...HCK). Decreased HCK expression disrupts CXCR4 signaling, impairing LSC self-renewal and BM homing. Therapeutically, we c...

Hematopoietic cell kinase activation in skeletal myocytes contributes to local …

Jin(F),He(R),Tang(Q),Yang(S),Qi(F) Biochem Biophys Res Commun 2026-08-27

...HCK activation. A rat MTrPs model was employed to explore the role of HCK. The HCK inhibitor A419259 was locally injecte...

Exogenous Quercetin Enhances Salt Tolerance in Apocynum venetum Seedlings: Insi…

Zhao(X),Buttar(ZA),Zhao(B),Jiang(L) Physiol Plant None

...HCK (control), HCKN (salt stress), Q3 (quercetin), and Q3 + N (quercetin + salt stress). These findings demonstrated tha...

Machine learning-based integration develops a novel lysosome-related prognostic…

Lu(L),Jiang(X),Lu(J),Lv(J) Discov Oncol 2026-06-23

...HCK, TCIRG1, CD1D, GPRASP1, ABCA1, and NAGA), and this model was further validated using GEO datasets. Significant diffe...

Constraining regulatory domain dynamics of the Src kinase Fgr increases ATP-sit…

Gonzalez-Areizaga(G),Shu(ST),Alvarado(JJ),Sh… Cell Rep 2026-06-23

...Hck, Lyn, and Fgr. Their modular SH3 and SH2 domains regulate kinase activity and signal transduction. Here, we show tha...

The myeloid SRC family kinase HCK regulates breast cancer growth by activating …

Murrey(MW),Poh(AR),Steer(JH),Rinaldi(C),Mouc… Front Immunol None

...HCK is known to regulate immune evasion, here we show that HCK promotes growth of an aggressively invasive mammary tumor...

Repurposing Product Nkabinde for Hepatitis B Virus Therapy: A Network Pharmacol…

Ugbaja(SC),Nkabinde(SA),Nkabinde(M),Gqaleni(… Pharmaceuticals (Basel) 2026-04-16

...HCK, EGFR, SYK, PIK3CA, PIK3CB, PIK3R1, and PTPN11). Gene Ontology and KEGG pathway enrichment were performed with an FD...

Sesquiterpenoids from the fruits of Alpinia oxyphylla showing renal protective …

Lu(BT),Liu(XN),Fang(HB),Zhu(YT),Zheng(YZ),Ch… Phytochemistry 2026-09-00

...HCK-8). RNA-seq analysis and target protein validation displayed that the anti-renal fibrosis activity of 1b was related...

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