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Human Neuraminidase 3 reduces the severity of Tay-Sachs disease symptoms in a...

Basırlı(H),Seyrantepe(V) Neurochem Int 2026-05-00

...HEXA and NEU3, Hexa-/-Neu3-/-, were generated. Abnormal GM2 accumulation was revealed in the brains of Hexa-/-Neu3-/- mi...

Structural analysis of clingstone and freestone peach (Prunus persica L.) pla...

Rizk(MS),Alsamman(AM),AbdAlla(HAM),El Zaya... J Genet Eng Biotechnol 2026-03-00

...hexa-nucleotide motifs.Variable Simple Sequence Repeats (SSRs) and codon usage patterns were identified as evolutionary ...

Effects of hydrogen-bonding properties of formamide on complex formation with...

Maseda(M),Takamuku(T) Phys Chem Chem Phys 2026-04-16

...hexa-FA-Zn2+ complexes are formed in solutions. The high hydrogen-bonding ability of FA molecules markedly reduces the s...

Rare-variant burden across lysosomal genes implicates sialylation and ganglio...

Senkevich(K),Parlar(SC),Chantereault(C),Li... medRxiv 2026-02-18

...HEXA, ST3GAL4 and SGPP1. Domain-based analyses identified a strong enrichment of nonsynonymous variants within the beta-...

Tay-Sachs disease models: From cellular and animal models to treatment perspe...

Suarez(DA),Leal(AF),Pachajoa(H),Granados-V... Mol Genet Metab 2026-06-00

...HEXA gene, resulting in deficient activity of β-hexosaminidase A (Hex-A). Loss of Hex-A function leads to the intralysos...

Synthesis and Hydrogen Adsorption Simulation of Carbonized Hyper-Cross-Linked...

Cheng(J),Cheng(X),Wang(Z),Wang(W) ACS Appl Mater Interfaces 2026-04-15

...hexa-heptagonal junction. The GCMC simulations indicate that the daidzein-derived HCPs reproduced the experimental trend...

Are unreported technical polychlorinated biphenyl formulations used in legacy...

Rex(KR),Subramani(S),Singh(I),Kanade(G),Wa... J Hazard Mater 2026-07-15

...hexa), accounting for more than 94% of total PCBs, with uniform distribution across urban and suburban/rural sites. No s...

Macrophage Proteomic Profiling Reveals Divergent TLR4-Dependent and -Independ...

Issara-Amphorn(J),Schoonmaker(JL),Bradfiel... Life (Basel) 2026-05-01

...hexa- to tetra-acylation. This alteration can limit binding to receptors and dampen subsequent immune signaling response...

Aza[6]- and Aza[7]helicenes: Synthesis and Reversible Protonation-Induced Tun...

Schumann(FR),Philippe(C),Weisenburger(P),C... JACS Au 2026-05-25

...hexa- and heptahelicenes. The synthesized azahelicenes exhibit remarkable fluorescence properties, including quantum yie...

Pre-clinical efficacy of a C4BP hexameric IgG Fc fusion protein against Neiss...

Shaughnessy(J),Du(J),Broden(MW),Gulati(S),... PLoS One None

...hexamerization. This molecule, called C4BP-Hexa IgG Fc, showed ~650-fold greater complement-dependent bactericidal activ...

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