...KRAS mutation compared to the paired primary, shifted from moderately to poorly differentiated morphology, and exhibited...
...KRAS-mutant colorectal cancer (K-CRC). A 4-anilinoquinazoline-based compound library was synthesized using automated and...
...KRAS-mutant (H358 and A549) lung adenocarcinoma cells, but not in the human bronchial epithelial cell line BEAS-2B. When...
...KRAS G12D inhibitor MRTX1133 has shown promising efficacy in preclinical models, its clinical efficacy as a single agent...
...KRAS mutations are central to PDAC initiation, growing evidence demonstrates that epigenetic dysregulation is a critical...
...KRAS mutations in thyroid lesions on fine-needle aspiration archival smears and compare them with histological diagnosis...
...KRAS G12C were more frequently observed in females, whereas no significant correlation between sex and other GA was obse...
...KRAS, NRAS, and HRAS (collectively RAS), several somatic mutations have been identified that alter this GTPase cycle to ...
...KRAS-G12C-mutated stage IVB lung adenocarcinoma initiated first-line treatment with carboplatin + pemetrexed + pembroliz...
...KRAS/NRAS/BRAF), and the tumor was microsatellite-stable (MSS). The patient received postoperative radiotherapy. At 6 mo...
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