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MIR27A rs895819 CC Genotype Severely Reduces miR-27a Plasma Expression Levels.

Ragia(G),Pallikarou(M),Michou(C),Manolopoulo… Genes (Basel) 2024-11-20

Background/Objectives:MIR27A rs895819 polymorphism has emerged as a potential additional pharmacogenomic marker of fluor...

Association between genetic variants in hsa-miR-27a and hsa-miR-146a genes and …

Rajovski(S),Matijašević-Joković(S),Milanović… J Med Biochem 2024-11-16

...miR27a (rs2910164) and hsa-miR-146a gene (rs895819) and male infertility in North Macedonian population, as well as to t...

The Association of pre-miR27a Gene Polymorphism and Clinicopathological Data in…

Sanguansin(S),Saelee(P),Kritsiriwuthinan(K),… Asian Pac J Cancer Prev 2023-06-01

MiR27a plays an important role in carcinogenesis, cell proliferation, apoptosis, invasion, migration and angiogenesis. S...

miRNA Expression Profiles of Mouse Round Spermatids in GRTH/DDX25-Mediated Sper…

Anbazhagan(R),Kavarthapu(R),Dale(R),Campbell… Cells 2023-00-27

...miR27a, miR150, miR196a, and miR328 that are relevant to spermatogenesis. mRNA-miRNA target analysis on these DE-miRNAs ...

Endurance-dependent urinary extracellular vesicle signature: shape, metabolic m…

Pietrangelo(T),Santangelo(C),Bondi(D),Cocci(… Pflugers Arch 2023-00-00

...miR27a-3p, miR133a, and miR206) also accounted for a differential signature. These miRNAs and guanosine in urinary EVs c...

Analysis of MIR27A (rs11671784) Variant Association with Systemic Lupus Erythem…

Khired(ZA),Kattan(SW),Alzahrani(AK),Milebary… Life (Basel) 2023-03-05

...MIR27A) rs11671784G/A variant with SLE risk/severity. One-hundred sixty-three adult patients with SLE and matched contro...

miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclas…

Wang(S),Maruyama(EO),Martinez(J),Lopes(J),Hs… Elife 2023-00-08

...MIR27a causing severe osteoporosis in mice. MIR27a affects osteoclast-mediated bone resorption but not osteoblast-mediat...

Potential Impact of PI3K-AKT Signaling Pathway Genes, KLF-14, MDM4, miRNAs 27a,…

Alzahrani(OR),Mir(R),Alatwi(HE),Hawsawi(YM),… Cancers (Basel) 2023-02-17

...miR27a-GG and miR-196a-CT gene variants were associated with the higher risk probability of BC and were strongly correla...

Andrographolide and pterostilbene inhibit adipocyte differentiation by downregu…

Kalamkar(SD),Bose(GS),Ghaskadbi(S),Mittal(S) Nat Prod Res 2023-00-00

...miR27a, whereas, PT upregulated SIRT1 which inhibits the expression of PPARγ. Thus, our results clearly demonstrate that...

Lipid Nanoparticles as a Shuttle for Anti-Adipogenic miRNAs to Human Adipocytes.

Schachner-Nedherer(AL),Fuchs(J),Vidakovic(I)… Pharmaceutics 2023-07-19

...miR27a) into a pegylated lipid nanoparticle (PEG-LNP) formulation by a single-step microfluidic-assisted synthesis step....

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