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Phosphatidylinositol 3-kinase-C2β inhibits cisplatin-mediated apoptosis via t...

Liu(Z),Sun(C),Zhang(Y),Ji(Z),Yang(G) J Int Med Res 2012-02-02

...PIK3C2B gene) reduced the sensitivity of ESCC to cisplatin, transfected Eca109 cells that overexpressed PIK3C2B were pr...

Identification of somatic mutations in non-small cell lung carcinomas using w...

Liu(Pengyuan),Morrison(Carl),Wang(Liang),X... Carcinogenesis 2012-10-16

...PIK3C2B, PIK3CG and ROCK2.

Analysis of human mini-exome sequencing data from Genetic Analysis Workshop 1...

Bueno Filho(Julio S),Morota(Gota),Tran(Quo... BMC Proc 2012-10-02

...PIK3C2B was correctly identified as being associated with affected status based on the simulation process. This project ...

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismat...

Diouf(Barthelemy),Cheng(Qing),Krynetskaia(... Nat Med 2011-12-07

...PIK3C2B); we also found these deletions in individuals with adult acute lymphoblastic leukemia (16%) and sporadic colore...

Myotubularin regulates Akt-dependent survival signaling via phosphatidylinosi...

Razidlo(Gina L),Katafiasz(Dawn),Taylor(Gre... J Biol Chem 2011-08-01

...PIK3C2B. Our findings are significant because they suggest that myotubularin regulates Akt activation via a cellular poo...

A survey of glioblastoma genomic amplifications and deletions.

Rao(Shailaja K),Edwards(Jennifer),Joshi(Av... J Neurooncol 2010-03-25

...PIK3C2B/MDM4 (12.9%). In the 22 GBM tumors, EGFR was amplified in 22.7% of surgical biopsies. The most common homozygous...

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of...

Koutros(Stella),Schumacher(Fredrick R),Hay... Cancer Res 2010-04-26

...PIK3C2B, PIK3AP1, PIK3C2A, PIK3CD, and PIK3R3) and prostate cancer risk in 8,309 cases and 9,286 controls. Odds ratios (...

Intratumoral patterns of genomic imbalance in glioblastomas.

Nobusawa(Sumihito),Lachuer(Joel),Wierinckx... Brain Pathol 2010-11-24

...PIK3C2B, MDM4), 4q11-q12 (KIT, PDGFRA), 7p12.1-11.2 (EGFR), 12q13.3-12q14.1 (GLI1, CDK4) and 12q15 (MDM2), and loss at 9...

Pathogenetic pathways leading to glioblastoma multiforme: association between...

Löw(Sarah),Vougioukas(Vassilios I),Hielsch... Anticancer Res 2009-03-03

...PIK3C2B) the expression of which significantly correlated with cellular resistance towards erlotinib.,Among the genes co...

Integrative genomic analysis of phosphatidylinositol 3'-kinase family identif...

Zhang(Lin),Huang(Jia),Yang(Nuo),Greshock(J... Clin Cancer Res 2007-12-14

...PIK3C2B (40.4%). Among those, only PIK3R3 had significantly up-regulated mRNA expression level in ovarian cancer compare...

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