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Development and validation of QuadraSynth ML: a novel classifier for sepsis p...

Shen(X),Huang(Y),Li(X),Li(Z),Du(J),Wen(D),... Front Cell Infect Microbiol None

...RalA in regulating inflammatory diseases has been noted, yet its specific relationship with sepsis remains unclear. This...

Transcriptomic Analysis Reveals Molecular Mechanisms of Fleeing, Adhesion, an...

Wu(G),Wu(H),Wang(X),Gao(Q),Zhao(C) Biology (Basel) 2026-06-22

...RaLA). These genes potentially contribute to sustaining the thanatosis pattern. These transcriptomic profiles provide no...

Single-Cell Transcriptomic Analysis Identifies an OLFM4-Associated Gastric Ca...

Chen(G),Wei(W),Li(D),Han(S),Schäfer(M),Hua... Biomolecules 2026-06-15

...RALA, and PCBD1) effectively stratified STAD patients and was associated with immune checkpoint expression and immune in...

The Involvement of the Small GTPase Rac1 in Insulin Signaling That Regulates ...

Takenaka(N),Sakata(M),Abe(Y),Iha(K),Satoh(... Int J Mol Sci 2026-06-20

...RalA axis in adipocytes of subcutaneous white adipose tissue (WAT) in living mice. The uptake of long-chain FAs by insul...

Regular exercise improves cardiac dysfunction in Drosophila by inhibiting exc...

Huang(W),Ding(M),Yi(Q),Li(Y),Gu(W),Zhang(P... Biochim Biophys Acta Mol Ba... 2026-10-00

...RalA -dependent manner within the myocardium. Mechanistically, RalA appeared to exert its effects not through traditiona...

mRNA vaccination using peptide nanoparticles triggers a strong immune respons...

King(E),Saha(C),Saleem(R),Jiang(B),O'Donog... Mol Ther Oncol 2026-06-18

...RALA for delivering mRNA encoding glypican 2 (GPC2), a potent tumor-associated antigen in neuroblastoma. These data outl...

UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice.

Zhang(B),He(Y),Su(T),Li(X),Zhang(X),Liu(R)... J Clin Invest 2026-09-15

...RalA (RalAG23V) or Mdivi-1 treatment. These findings support RalA inhibition as a therapeutic strategy for enhancing mit...

CRISPR-Cas9 mediated RALA knockout and reconstitution: insights into the dete...

Konde(MV),Inchanalkar(S),Sherkhane(TM),Des... Biol Open 2025-07-15

...RALA and S194A-RALA mutants, showed no effect on RALA activation. Tumor growth was, however, restored partly by WT-RALA,...

A novel 20 (R) dammarane panaxadiol-indole-2 ',3' -dione derivative was found...

Tan(H),Lv(L),Chai(Y),Chai(J),Huang(C),Han(... Eur J Med Chem 2025-11-15

...RalA/EMT pathway by inhibiting EGFR rather than RalB, disrupts the formation of filamentate feet and cytoskeletal remode...

Unimolecular Micelle for MLN8237 Delivery to Target AURKA-RalA Crosstalk for ...

Singh(K),Pathan(S),Malhotra(M),Jayakannan(... Biomacromolecules 2025-08-11

...RalA phosphorylation (pSer194RalA) in both tumors. Together, they highlight the therapeutic potential of NPMLN in target...

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