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Kuo(YT),Wang(HC),Shan(YS) Cell Death Discov 2026-03-28

...RhoA, increasing its stability and thereby sustaining ROCK2 phosphorylation, which contributes to occludin degradation. ...

He(B),Yang(W),Yang(J),Zhang(J) Brain Res 2026-07-15

...RhoA/ROCK-related signaling were assessed by immunofluorescence and Western blot. In vivo, a rat contusion SCI model rec...

Wen(W),Xia(J),Liu(G),Wang(C) Drug Des Devel Ther None

...RhoA/ROCK and Mst1-JNK, have been identified as critical mediators of its hepatoprotective actions. Toxicological data i...

Pérez-Díaz(R),Garrido-Casado(M),Ramos-Sola... Biophys Rev 2026-02-00

...RhoA/ROCK, organizing myosin II activity in space and time and enabling the emergence of stress fibers, junctional belts...

Fadhal(E),Mwambene(E) J Vis Exp 2026-03-13

...RHOA, MAP2K1, EGFR, CDC42, and ANGPT1 were identified as central players in processes including apoptosis resistance, me...

Lv(QH),Hu(T),Xu(JP),Xu(XY),Ouyang(J),Wu(D)... J Ethnopharmacol 2026-07-15

...RhoA in microglia is decreased after ischemia-reperfusion injury, and TXC upregulated RhoA, inhibited Rock2/ASC-mediated...

Kuchovska(E),Bartmann(K),Raad(G),Schade(M)... Adv Sci (Weinh) 2026-07-00

...RhoA and mitochondrial complex I pathways is associated with the broadest phenotypic responses, influencing five KNDPs e...

Nguyen(LTK),Tran(DN),Nahar(S),Kim(TH),Jeon... FASEB J 2026-04-30

...RHOA, AMPK-NOTCH1-HEY1, and oxidative stress-induced senescence signaling, implicating dysregulation of cytoskeletal rem...

Koo(TY),Ho(CS),Yip(HY),Chung(CY) STAR Protoc 2026-06-19

Ras homolog family member A (RhoA) is a therapeutic hotspot in many cancers but remains undruggable. Here, we present a ...

Abraham(S),Zhu(C),Le(LHS),Alugubelli(YR),N... Biochemistry 2026-05-05

Mutant RhoA G17V is a clinically significant yet historically undruggable oncogenic GTPase that drives angioimmunoblasti...