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Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.

Kröcher(Tim),Malinovskaja(Kristina),Jürgen... Brain Struct Funct 2015-08-28

...St8sia2 (-/-) mice. Both polyST-deficient lines were impaired in short- and long-term recognition memory, but only St8si...

Genetics of psychotropic medication induced side effects in two independent s...

Fabbri(Chiara),Souery(Daniel),Calati(Raffa... J Neural Transm (Vienna) 2015-08-26

...ST8SIA2), second messenger cascades (GSK3B, MAPK1, and CREB1), circadian rhythms (RORA), transcription (SP4, ZNF804A), a...

St8sia2 deficiency plus juvenile cannabis exposure in mice synergistically af...

Tantra(Martesa),Kröcher(Tim),Papiol(Sergi)... Behav Brain Res 2015-07-24

...St8sia2(+/+)) (7mg/kg every other day over 3 weeks) did not appreciably affect cognition. St8sia2(-/-) mice, however, di...

Characterization of a 520 kb deletion on chromosome 15q26.1 including ST8SIA2...

Kamien(Benjamin),Harraway(James),Lundie(Be... Am J Med Genet A 2014-11-03

...ST8SIA2, C15orf32, and FAM174B. Alpha-2,8-Sialyltransferase 2 (ST8SIA2) is expressed in the developing brain and appears...

Characterisation of genetic variation in ST8SIA2 and its interaction region i...

Shaw(Alex D),Tiwari(Yash),Kaplan(Warren),H... PLoS One 2014-11-07

...ST8SIA2 expression. We calculated nucleotide diversity within ST8SIA2 on specific haplotypes, finding that the diversity...

Modification of sialylation mediates the invasive properties and chemosensiti...

Zhao(Yongfu),Li(Yanping),Ma(Hongye),Dong(W... Mol Cell Proteomics 2014-10-09

...ST8SIA2, were detected as overexpressed in MHCC97H and MHCC97L cells. The altered expression levels of ST6GAL1 and ST8SI...

Polysialic acid/neural cell adhesion molecule modulates the formation of duct...

Tsuchiya(Atsunori),Lu(Wei-Yu),Weinhold(Bir... Hepatology 2014-12-30

...St8sia2+/-4+/- and St8sia2-/-4-/- mice) caused abnormal bile duct development. In normal liver, there is minimal polySia...

EPAC-STX interaction may play a role in neurodevelopment/neurogenesis.

Razmi(Ali),Jahanabadi(Samane),Sahebgharani... Med Hypotheses 2014-02-03

...ST8SIA2), the embryonic active isoform, and PST (ST8SIA4), expressed in adults CNS. Additionally, cAMP concludes to acti...

Transcription factor AP-2delta regulates the expression of polysialyltransfer...

Li(Xiaodong),Persad(Amit R L),Monckton(Eli... FEBS Lett 2014-04-14

...ST8SIA2 promoter. We propose that up-regulation of ST8SIA2 upon AP-2δ overexpression in retina increases ectopic polysia...

Cyclic AMP pathway modifies memory through neural cell adhesion molecule alte...

Razmi(Ali),Sahebgharani(Mousa),Khani(Moham... Acta Med Iran 2014-09-11

...St8sia2 (the polysialyltransferase isoforms) were altered. The mRNA levels of St8sia4 was down-regulated by 8-Br-cAMP, R...

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