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TWEAK is increased in ulcerative colitis and contributes to fibroblast-mediat...

Matellan(C),Raphael(B),Jones(GR),Nwaeziegw... J Crohns Colitis 2026-02-05

...TNFSF12) can induce an ulcerative colitis (UC)-like inflammatory profile in colonic fibroblasts in vitro, in turn promot...

APOE+ macrophages induce tumor cell metastatic characteristics via TNFSF12/TN...

Song(C),Sun(H),Gan(W),Liu(Q),Wu(L),Zhu(M),... Cancer Cell Int 2026-05-20

...TNFSF12 in the tumor microenvironment. TNFSF12 acted on TNFRSF12A-expressing CRC cells and was associated with BCL2L1 up...

[Bidirectional two-sample MR analysis of causal relationships between human i...

Wang(SS),Xiao(K),Xiao(HT),Han(DW),Zhang(J)... Zhonghua Shao Shang Yu Chua... 2026-07-20

...TNFSF12), programmed death-ligand 1 (PD-L1), interleukin-17C (IL-17C), LIF receptor (LIFR), osteoprotegerin (OPG), and f...

Inflammatory Cytokines May Mediate the Causal Relationship between Metabolite...

Liu(H),Zhong(Z),Ning(S) Curr Med Chem 2026-06-23

...TNFSF12 served as risk factors. Mediation analysis revealed that these cytokines partially mediated the associations bet...

Immune-Mediated Gut-Lung Axis in IPF: Bidirectional Mendelian Randomization a...

Zhao(J),Liu(Z),Kuang(L),Dong(A),Gong(H),Yi... Endocr Metab Immune Disord ... 2026-06-03

...TNFSF12 (10.8%), and CCL25 (4.94%). Immune cells, such as HLA-DR+ CD33- myeloid cells, modulated IPF via plasma metaboli...

Environmental Pollutant Tetrachloro-1,4-benzoquinone Exerts Neurotoxicity and...

Rong(C),Wei(Z),Xie(D),Wang(Q),Ren(H),Wang(... Curr Top Med Chem 2026-06-09

...TNFSF12, NFRSF11B has a causal relationship with Alzheimer's disease. TCBQ can promote neurotoxicity by increasing infla...

Investigating the causal relationship between circulating inflammatory protei...

He(S),Wei(M),Meng(D),Lv(Z),Yang(G),Wang(Z) Hear Res 2025-09-00

...TNFSF12 are positively associated with tinnitus risk, while CD40L and IL-10 exhibit protective effects. Reverse MR analy...

Circulating Plasma Proteins as Biomarkers for Immunotherapy Toxicity: Insight...

Tang(L),He(W),Hu(H),Liu(J),Li(Z) Biomedicines 2025-07-14

...TNFSF12 (all-grade) and ADA/CCL25 (high-grade) as therapeutic targets (PPH4 > 0.7). CXCL9/TNFSF12 (all-grade) and CCL25 ...

A multi-omics approach reveals dysregulated TNF-related signaling pathways in...

Nour-Eldine(W),Ltaief(SM),Ouararhni(K),Abd... Genes Immun 2025-10-00

...TNFSF12 (TWEAK) in plasma of individuals with ASD. Single-cell RNA-seq revealed that B cells, CD4 T cells, and NK cells ...

Dissecting causal networks of inflammatory factors and metabolites in heart f...

Guan(X),Wang(Y) Medicine (Baltimore) 2025-08-08

...TNFSF12: OR = 0.933, uPA: OR = 0.927). More than 13 metabolites (out of 1400) showed robust associations with HF risk, w...

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