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Anti-inflammatory CAR-microglia targeting Aβ for Alzheimer's disease therapy.

Ding(X),Hu(X),Xue(W),An(Y),Cheng(W),Zhang(... Front Immunol None

...TYRO3, AXL, and MERTK), which are key regulators of efferocytosis and anti-inflammatory responses. The resulting Aβ-targ...

Anticancer Effects of Cucurbitacin B and Meleagrin Associated with TYRO3 Down...

Ilhan(RS),Gurboga(M),Sekerler(T),Ulupinar(... Int J Mol Sci 2026-07-28

...TYRO3 expression were evaluated using functional and expression-based analyses. Both compounds modulated TYRO3 expressio...

Ferroptosis-Related Diagnostic Biomarkers in Diabetic Kidney Disease: A Multi...

Li(X),Hong(H),Li(H),Fang(Z),Wang(J),Wang(X... J Inflamm Res None

...TYRO3 enrichment in podocytes, with remodeling of TYRO3-associated intercellular communication in DKD. In DKD rat kidney...

Therapeutic potential of TAM receptors in autoimmune diseases: insights from ...

Adedayo(SI),Gegele(TA),Adeshina(KA),Olukad... Oxf Open Immunol None

...Tyro3, Axl, and Mertk, belong to the receptor tyrosine kinase family and are activated by binding of their cognate ligan...

Injectable hybrid hydrogels enhance macrophage communication via second messe...

Du(Y),Huang(F),Chen(H),Ling(S),Wang(H),Zhu... J Control Release 2026-03-10

...Tyro3-Axl-Mer receptors, RAC1, and cAMP-related signaling pathways, significantly enhancing efferocytosis-related macrop...

Targeting TYRO3 attenuates apoptotic cell-driven cancer stemness in triple ne...

Tran(PT),Shim(WS),Jeong(WC),Park(J),Kim(MJ... Cell Commun Signal 2026-04-23

...TYRO3/YAP signaling axis, TYRO3 and YAP knockdown models were established by CRISPR/Cas9 or retroviral system. The anti-...

Novel Efferocytosis-Related Prognostic Signature for Hepatocellular Carcinoma...

Xie(X),Zheng(B) Gut Liver 2026-05-07

...TYRO3, CD14, and TREM2 was established and validated for HCC patients, including those who underwent TACE treatment. Hig...

TAM receptor tyrosine kinases as potential mediators of the non-lytic spread ...

Moran(SJ),Starbird(CA) Biochem Soc Trans 2026-05-27

Tyro3, Axl, and Mer are receptor tyrosine kinases that comprise the TAM receptor family. These receptors, originally ide...

Sublytic pyroptosis blocks Schwann cell remyelination through caspase-1-media...

Lu(X),Han(Y),Li(D),Li(S),Li(Z),Li(Y),Liu(Q... J Neuroinflammation 2026-02-27

...Tyro3 receptor at Asp495, detaching the intracellular kinase domain and abolishing receptor function. This proteolytic i...

Tyro3 facilitates cytoplasmic delivery of extracellular vesicle contents and ...

Koyama(T),Kojima(K),Maeda(K),Matsui(T),Kos... PLoS One None

...Tyro3 binding to sEVs was enhanced by Gas6 and Pros1, and that Tyro3 also associated with phosphatidylserine (PS) and ph...

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