Yamanaka(S),Johnson(O N),Norflus(F),Boles(... Genomics 1994-11-30

Two genes, HEXA and HEXB, encode the alpha- and beta-subunits, respectively, of human beta-hexosaminidase. In the mouse,...

Horii(A),Han(H J),Sasaki(S),Shimada(M),Nak... Biochem Biophys Res Commun 1994-12-22

...hexB, has also been proven to be related to the DNA mismatch repair system. As the first step to understand whether huma...

Sagherian(C),Poroszlay(S),Vavougios(G),Mah... Biochem Cell Biol 1994-04-14

...HEXB genes, respectively. Extensive homology in both the gene structures and deduced primary sequences demonstrate their...

Triggs-Raine(B L),Benoit(G),Salo(T J),Tras... Biochim Biophys Acta 1994-11-23

...HEXB promoter. Analysis of the tissue distribution of the HEXB mRNA in 129/Sv male mice revealed up to 28-fold tissue-sp...

Prolla(T A),Christie(D M),Liskay(R M) Mol Cell Biol 1994-01-21

...HexB) and S. cerevisiae yeast (PMS1). Disruption of the MLH1 gene results in elevated spontaneous mutation rates during ...

Guérin(G),Eggen(A),Vaiman(D),Nocart(M),Lau... Anim Genet 1994-05-13

...HEXB and HTR1A) and two by polymerase chain reaction (PCR) amplification (HRH1 and ETH1112). These loci were assigned to...

Zhang(Z X),Wakamatsu(N),Mules(E H),Thomas(... Hum Mol Genet 1994-05-23

Sandhoff disease is an autosomal recessive lysosomal storage disease resulting from mutations of the HEXB gene encoding ...

Muldoon(L L),Neuwelt(E A),Pagel(M A),Weiss... Am J Pathol 1994-06-06

...HEXB gene encoding the beta subunit of the beta-hexosaminidases. In the present report, we examined the brain and liver ...

Rogers(J),Kidd(K K) Am J Phys Anthropol 1993-05-17

...HEXB, VIM, and APOB) for restriction fragment length polymorphisms (RFLP). A total of 14 polymorphisms, at least one at ...

Eguchi(I),Wakamatsu(N),Nakano(R),Tsuji(S) Nihon Rinsho 1993-11-22

...HEXB gene. Defects in the beta subunit lead to Sandhoff disease. Patients with the defect lack the activity or formation...