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Lohneis(Philipp),Darb-Esfahani(Silvia),Die... Anticancer Res 2016-02-08

...PDK1) mediates the cellular effects of various growth factors. Increased PDK1 expression is present in various cancers, ...

Song(Guo-Qing),Zhao(Yi) Am J Transl Res 2016-04-12

...PDK1) in breast cancer tissues were higher than those in corresponding noncancerous tissues. HK2, PKM2, and PDK1 express...

Liu(Yan),Li(Xuemei),Xie(Chen),Luo(Xiuzhen)... PLoS One 2016-08-18

...PDK1 were confirmed by western blot analysis. In conclusion, this study demonstrated the potential protective effects of...

Lo(Hsin-Yi),Li(Chia-Cheng),Ho(Tin-Yun),Hsi... Food Chem 2016-10-31

...PDK1 and Akt, induced the expression of glucose transporter 4, and stimulated both the uptake of glucose in cells and th...

Gopal(Udhayakumar),Gonzalez-Gronow(Mario),... J Biol Chem 2016-11-10

...PDK1) to induce phosphorylation of PLK1, which in turn induces c-MYC transcription. We demonstrate that PLK1 binds direc...

Zhang(Shao-Lin),Hu(Xiaohui),Zhang(Wen),Tam... J Med Chem 2016-09-27

...PDK1).

García-Marqués(Sara),Randez-Gil(Francisca)... Biochim Biophys Acta 2016-07-19

...PDK1 orthologous Pkh1/2p, and requires the function of protein effectors, among them Nce102p, a component of the sphingo...

Sun(Wenyi),Xie(Zuoquan),Liu(Yifu),Zhao(Dan... Cancer Res 2016-02-29

...PDK1 enzymatic activity. Notably, cells with a higher dependency on glycolysis were more sensitive to PDK1 inhibition, r...

Shimobaba(Shun),Taga(Saeko),Akizuki(Risa),... Biochim Biophys Acta 2016-07-19

...PDK1 and suppressed the nuclear localization of PDK1. We suggest that claudin-18 suppresses the abnormal proliferation a...

Shao(Genbao),Wang(Jie),Li(Yuanxia),Liu(Xiu... Sci Rep 2016-09-08

...PDK1/AKT pathway mediates the EGF-induced expression of LSD1 and cell migration. Significantly, LSD1 knockdown or inhibi...