...TEAD4 (TEA domain transcription factor 4) to regulate chromatin accessibility at target gene loci through histone acetyl...
...TEAD4 complex transcriptionally activated LEF1, a central regulator of Wnt signaling. LEF1 deficiency phenocopied YAP lo...
...TEAD4⋅Yap1. Virtual screening of conformationally restricted compounds targeting uPAR⋅uPA and TEAD4⋅Yap1 followed by exp...
...TEAD4 requires GR for its expression and for the ability to bind its own promoter and the hotspot region of Pparg2 gene ...
The transcriptional activity of TEAD4 (transcriptional enhancer associated domain proteins), one of the final effectors ...
...TEAD4, ILK and a-SMA expression were evaluated by immunohistochemistry in keloids (n = 55), hypertrophic scars (n = 38) ...
...TEAD4 and KLF5 function to mediate cell polarization. Notably, we found that maternal retinoic acid metabolism regulates...
...TEAD4/YAP1 binding in a nucleosome-range and distance-dependent manner, driving synergistic enhancer activation. We also...
...TEAD4 and CEBPA and promotes the cooperative activation of Pdk4 expression. Functional studies identify PDK4 as a downst...
...TEAD4 redistribution and super-enhancer rewiring. These findings reveal a YAP/TAZ-TEAD4 axis controlling tumor cell plas...
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