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Expression profiles of protein tyrosine kinase genes in human embryonic stem ...

Son(Mi-Young),Kim(Janghwan),Han(Hyo-Won),W... Reproduction 2008-12-31

...TYRO3, SRC, and GSK3A were consistently downregulated in two hESC lines. Western blot analysis showed that the transcrip...

Localization and signaling of the receptor protein tyrosine kinase Tyro3 in c...

Prieto(A L),O'Dell(S),Varnum(B),Lai(C) Neuroscience 2008-04-03

...Tyro3 is one of three RPTKs belonging to the "TAM" receptor family, which also includes Axl and Mer. Tyro3 is the most w...

[Gas-6 and protein S: vitamin K-dependent factors and ligands for the TAM tyr...

Benzakour(Omar),Gely(Aurore),Lara(Romain),... Med Sci (Paris) 2008-01-31

...Tyro3/Axl/Mer family of related tyrosine kinase receptors has opened up a new area of research. Moreover, the phenotypes...

Novel splice donor site mutation in MERTK gene associated with retinitis pigm...

Brea-Fernández(A J),Pomares(E),Brión(M J),... Br J Ophthalmol 2008-10-21

...TYRO3 receptor kinase family, have been associated with disruption of the Retinal Pigment Epithelium (RPE) phagocytosis ...

Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and...

Maree(Andrew O),Jneid(Hani),Palacios(Igor ... Curr Pharm Des 2007-11-07

...Tyro3 and Mer whose signaling has been implicated in cell growth, survival, adhesion and migration. Although a secreted ...

Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in cl...

Seitz(Heather M),Camenisch(Todd D),Lemke(G... J Immunol 2007-06-18

...Tyro3. The slower ingestion may be due to lower DC expression of Axl and Tyro3 or absence of GAS6 expression, a known li...

Structural basis for Gas6-Axl signalling.

Sasaki(Takako),Knyazev(Pjotr G),Clout(Naom... EMBO J 2006-03-07

...Tyro3 and Mer. Specificity at the major contact is suggested to result from the segregation of charged and apolar residu...

Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice ...

Radic(Marko Z),Shah(Kinjal),Zhang(Wenguang... J Immunol 2006-02-16

...Tyro3, Axl, and Mer. Deficient mice exhibit an increased abundance of apoptotic cells in tissues and manifest diverse au...

Role of the growth arrest-specific gene 6 (gas6) product in thrombus stabiliz...

Saller(François),Burnier(Laurent),Schapira... Blood Cells Mol Dis 2006-11-03

...Tyro3 family, mice deficient in any one of the Gas6 receptors (Gas6-Rs: Tyro3, Axl, or Mer) were submitted to thrombosis...

Tyro3 family-mediated cell entry of Ebola and Marburg viruses.

Shimojima(Masayuki),Takada(Ayato),Ebihara(... J Virol 2006-11-02

...Tyro3 receptor tyrosine kinase family-Axl, Dtk, and Mer-in cell entry of filoviruses. Ectopic expression of these family...

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