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Total absence of the alpha2(I) chain of collagen type I causes a rare form of E…

Malfait(F),Symoens(S),Coucke(P),Nunes(L),De … J Med Genet 2006-08-09

...COL1A1 or COL1A2 gene encoding the alpha1 and alpha2 chain of type I collagen generally cause either osteogenesis imperf...

Fli1 and Ets1 have distinct roles in connective tissue growth factor/CCN2 gene …

Nakerakanti(Sashidhar S),Kapanadze(Bagrat),Y… J Biol Chem 2006-10-10

...COL1A1 and COL1A2 genes and down-regulation of the MMP1 gene. Thus, inhibition of Fli1 recapitulated some of the key eff...

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia.

Li(Ji),Sarosi(Ildiko),Cattley(Russell C),Pre… Bone 2006-12-12

...Col1A1 3.6 kb promoter) yielded osteopenia with forelimb deformities and hairlessness, while expression restricted to os...

Mutation analysis of COL1A1 and COL1A2 in patients diagnosed with osteogenesis …

Pollitt(Rebecca),McMahon(Robert),Nunn(Janice… Hum Mutat 2006-08-07

...COL1A1 or COL1A2 genes which encode the two alpha chains of type I collagen, the major component of the bone matrix. Ana...

Interleukin-7 modulates extracellular matrix production and TGF-beta signaling …

Yamanaka(Osamu),Saika(Shizuya),Ikeda(Kazuo),… Curr Eye Res 2006-08-08

...col1A1) m-RNA by using real-time RT-PCR.,IL-7 reduced the ECM production much more markedly in the cells treated with TG...

Interferon-gamma induces major histocompatibility class II transactivator (CIIT…

Butticè(Giovanna),Miller(Janice),Wang(Lin),S… Circ Res 2006-03-30

...COL1A1 and COL1A2) and activates MHC II promoter. Levels of CIITA and RFX5 increase in the nucleus of cells treated with...

Mice with a deletion in the first intron of the Col1a1 gene develop dissection …

Marjamaa(J),Tulamo(R),Abo-Ramadan(U),Hakovir… Magn Reson Med 2006-07-07

Deletion of the majority of the first intron of the Col1a1 gene in mice leads to decreased type I collagen synthesis and...

Proteasome blockade exerts an antifibrotic activity by coordinately down-regula…

Fineschi(Serena),Reith(Walter),Guerne(Pierre… FASEB J 2006-04-21

...COL1A1, TIMP-1, and MMP-1 paralleled protein levels. These effects were dominant over the profibrotic properties of TGF-...

MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive mo…

Sakai(Norihiko),Wada(Takashi),Furuichi(Kengo… J Leukoc Biol 2006-05-02

...COL1A1) as well as protein synthesis. Similarly, the expression of MCP-1 and CCR2 was enhanced by the stimulation with M...

Regulation of procollagen amino-propeptide processing during mouse embryogenesi…

Le Goff(Carine),Somerville(Robert P T),Keste… Development 2006-06-13

...Col1a1, Col2a1 and Col3a1, during mouse embryogenesis, demonstrated distinct tissue-specific, overlapping expression pat...

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