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In vitro Isolation and Culturing of Mouse Primary Chondrocytes for Cartilage ...

Song(Q),Xu(Y),Xie(Y),Huo(X),Sun(J),Zhao(Y)... J Vis Exp 2025-09-23

...Col2a1) and increased Matrix Metallopeptidase 13 (Mmp13) expression, confirming that isolated chondrocytes respond to in...

In vivo direct lentiviral gene therapy improves disease pathology in a mucopo...

Celik(B),Rintz(E),Khan(S),Leal(AF),Nidhi(F... Mol Ther Methods Clin Dev 2025-09-11

...COL2A1), and Mac-1 integrin subunit (CD11b). At the newborn stage and 4 weeks, Galns-knockout mice received intravenous ...

Structural features of the articular disc of the rat temporomandibular joint:...

Shibata(S),Takahashi(M),Shibui(T),Seki-Kis... J Oral Biosci 2025-12-00

...Col2a1 mRNA was analyzed by in situ hybridization using antisense cRNA probes. Other samples were analyzed by transmissi...

Mettl1-mediated m7G modification of Fgfr2 regulates osteogenic and chondrogen...

Li(Q),Zhang(Y),Ji(P),Zhang(Y),Jiang(J),Jin... Int J Biol Sci 2025-00-00

...Col2a1. Pharmacological reactivation of Fgfr2 signaling rescues the defects caused by Mettl1 deletion. Our findings high...

Interaction Between Human Skeletal and Mesenchymal Stem Cells Under Physioxia...

Azain(CM),Santamaría Durán(AN),Castañeda(T... Cells 2025-09-11

...COL2A1, COL10A1, PRG4, and PDPN), chondrocyte-associated antigens (CD44, CD105, CD146, and PDPN), and cartilage ECM prot...

Detection of the Candidate Genes of Economically Important Traits in Dorper S...

Wang(Z),Liu(Z),Sun(H),Bai(C),Pi(T),Ma(H),Z... Vet Sci 2025-09-14

...COL2A1, DAB2IP, EPYC, TSPAN18, WNT1, CTPS1, FBXW7, INSR, S100A6, SOCS2), energy metabolism (ACSS3, ADGRE3, CPT2, GCGR, P...

Exploring Mechanotransduction and Inflammation in Human Cartilaginous Endplat...

Crump(KB),Chapallaz(C),Alminnawi(A),Bermud... Gels 2025-09-12

...COL2A1. No significant changes were seen due to dynamic compression, suggesting addition of collagen to agarose was not ...

Benzophenone-3 drives osteoarthritis pathogenesis by regulating chondrocyte s...

Zhu(Z),Wang(C),Wei(S),Wu(R),Zhao(W),Zhao(X... Chem Biol Interact 2025-11-01

...Col2a1). Notably, in human C28/I2 chondrocytes, BP-3 significantly disrupted ECM balance evidenced by increased MMPs and...

3D Surface-Patterned Hyaluronic Acid Hydrogels: Customizable Platforms for En...

Natarajan(A),Sudha(A),Dean(D),Vijayan(VM) ACS Appl Mater Interfaces 2025-09-24

...COL2A1, ACAN) and hypertrophic (COL10A1) markers. Honeycomb hydrogels exhibited superior stiffness, swelling resistance,...

FoxO1/PINK1/Parkin-dependent mitophagy mediates the chondroprotective effect ...

Bocheng(L),Yongfu(C),Junjie(C),Ziqi(L),Lin... Phytomedicine 2025-11-25

...COL2A1 and the anti-apoptotic protein BCL2, along with downregulation of catabolic factors (MMP13, IL-1β). Mechanistical...

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