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Kumar(R),Thian(J),Toh(JDW),Farzana(N),Sun(... ACS Med Chem Lett 2026-03-12

...KRAS mutant Non-Small Cell Lung Cancer (NSCLC) cells, which may eventually overcome drug resistance associated with the ...

Meng(L),Liang(SH) ACS Med Chem Lett 2026-03-12

...KRAS oncogene, which is the most frequently mutated in human cancers. These compounds, along with their pharmaceutical c...

Huang(X),Huang(J),Hong(Q),Ou(X),Li(R),Zong... ACS Med Chem Lett 2026-03-12

...KRAS reactivation. SOS1, a key guanine nucleotide exchange factor involved in KRAS activation and implicated in various ...

Hill(AL),Cullinan(DR),Ahmed(O),Wesson(R),S... J Am Coll Surg 2026-08-01

...KRAS mutation was statistically significantly associated with recurrence (p = 0.01). Transplant was performed a median o...

Wei(T),Zhang(J),Chatzipanagiotou(OP),Guo(S... Eur J Surg Oncol 2026-05-00

...KRAS mutations occurred in 29% of profiled patients, which was associated with reduced RFS (mutant vs. wild-type KRAS: m...

Wei(F),Zou(Q),An(J),Zhang(T),Sun(Q),Li(X),... Gastroenterology 2026-07-00

...Kras mutation induced ADM in pancreas. Metaplastic epithelial cells actively induced neuritogenesis, and neural remodeli...

Ichikawa(T),Kudo(K),Takigawa(Y),Osedo(T),S... Intern Med 2026-03-17

...KRAS) mutations are poor prognostic factors in non-small cell lung cancer. We report two cases of metastatic KRAS G12C-p...

Ahn(KS),O'Brien(D),Kang(YN),Mounajjed(T),L... HPB (Oxford) 2026-06-00

...KRAS-associated signaling pathways in the large duct type. Mutation analysis showed that KRAS and PIK3CA mutations were ...

González Uribe(A),González Sánchez(VL),Bla... Cureus 2026-02-00

...KRAS G12V mutation. During follow-up, she presented with vulvar, perineal, inguinal, and gluteal erythematous papules, n...

Ghosh(D),Kazi(A),Vasiyani(HKK),Vudatha(V),... Eur J Cancer 2026-03-11

...KRAS G12D inhibitor MRTX1133 represents a major advance in targeting oncogenic KRAS, but adaptive resistance driven by E...