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Lin(Yuan-xiang),Lin(Kun),Kang(De-zhi),Liu(... Epilepsy Res 2015-12-21

...PDK1-AKT-mTOR activation differentiates balloon cells from dysmorphic neurons. We used immunohistochemistry with antibod...

No(Yi Ran),He(Peijian),Yoo(Byong Kwon),Yun... Am J Physiol Cell Physiol 2015-09-14

...PDK1) autophosphorylation, and knockdown of Pyk2 or PDK1 mitigated LPA-induced phosphorylation of RSK and stimulation of...

Cotroneo(Emanuele),Ashek(Ali),Wang(Lei),Wh... Circ Res 2015-07-21

...pdk1, lung fluorine-18-labeled 2-fluoro-2-deoxyglucose ligand uptake was significantly increased in IDD rats. The hemody...

Konno(Masamitsu),Doki(Yuichiro),Mori(Masak... Nihon Rinsho 2015-08-06

...PDK1 expression by controlling its transcription. PKM2 confers malignant potential by controlling both metabolism and tr...

Tan(Zheng),Xie(Na),Cui(Huachun),Moellering... J Immunol 2015-08-20

...PDK1 diminished M1, whereas it enhanced M2 activation of macrophages. Mechanistically, PDK1 knockdown led to diminished ...

Karlsson(Isabella),Zhou(Xin),Thomas(Raquel... Vasc Cell 2015-05-27

...PDK1 activation and sucrose density gradient fractionation was performed to examine recruitment of PTEN to membrane raft...

Qi(Lei),Toyoda(Hidemi),Xu(Dong-Qing),Zhou(... Cancer Cell Int 2015-09-30

...PDK1 and mTOR, respectively, and induced higher G0-G1 ratio in LAN-1-MK than that in LAN-1 as well. PDK1 and mTOR inhibi...

Hossen(Muhammad Jahangir),Kim(Seung Cheol)... Expert Opin Ther Pat 2015-12-22

...PDK1 activators and inhibitors and restates the selective patents published before September 2011. PDK1 modulators are o...

Stolze(Britta),Reinhart(Stefanie),Bullling... Sci Rep 2015-12-02

...PDK1, and AKT. KRAS-G12D, G12V, G13D, and K117N mediated EGF-independent proliferation, whereas anchorage-independent gr...

Leung(Lana),Bhakta(Ashesh),Cotangco(Kather... Cell Physiol Biochem 2015-12-21

...PDK1, p-PTEN, p-c-Raf, p-GSK-3β, rap-1 and ERK1/2. All blots were normalized to GAPDH levels (n = 6-18/group).,These dat...