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Gene transfer investigations of p56-LCK function in IL-2-dependent T-cell lin...

Taichman(R S),Torigoe(T),Tanaka(S),Miyashi... Cytokine 1993-04-08

...FYN, p62-YES) and that (ii) IL-2-mediated regulation of p56-LCK correlated with IL-2-driven proliferation of these T cel...

Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated t...

Umemori(H),Wanaka(A),Kato(H),Takeuchi(M),T... Brain Res Mol Brain Res 1993-04-01

...Fyn and Lyn are expressed in lymphocytes. Fyn is expressed in T cells at elevated levels and is associated with the T ce...

Impaired long-term potentiation, spatial learning, and hippocampal developmen...

Grant(S G),O'Dell(T J),Karl(K A),Stein(P L... Science 1993-01-25

...fyn mutants showed impaired spatial learning, consistent with a functional link between LTP and learning. Although fyn i...

Expression and characterization of the p85 subunit of the phosphatidylinosito...

Gout(I),Dhand(R),Panayotou(G),Fry(M J),Hil... Biochem J 1993-01-08

...fyn. Both p85 alpha and p85 beta form tight complexes with these protein-tyrosine kinases as measured by immunoprecipita...

Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal t...

Mills(G B),Arima(N),May(C),Hill(M),Schmand... Int Immunol 1993-02-04

...FYN in IL-2 signal transduction. However, in this report, we now demonstrate that neither LCK nor FYN are obligatory for...

T-lymphocyte proliferation: tyrosine kinases in interleukin 2 signal transduc...

Schmandt(R),Fung(M),Arima(N),Zhang(N),Leun... Baillieres Clin Haematol 1993-01-08

...fyn, fgr, ltk, hck and lyn can be ruled out as obligatory mediators. Using methods to clone tyrosine kinases from T cell...

Engagement of the TcR/CD3 complex stimulates p59fyn(T) activity: detection of...

da Silva(A J),Yamamoto(M),Zalvan(C H),Rudd... Mol Immunol 1993-01-04

...fyn(T) could account for this cascade, TcR/CD3 driven stimulation of p59fyn(T) activity has not been demonstrated. In th...

Phosphotyrosine-modified proteins are localized in Müller cells of the chick ...

Biscardi(J S),Cooper(N G),Maness(P F) Exp Eye Res 1993-05-18

...fyn and yes proto-oncogenes were expressed in Müller glia-enriched cultures, and could contribute to the observed protei...

Tyrosine phosphorylation in early embryonic growth cones.

Bixby(J L),Jhabvala(P) J Neurosci 1993-09-02

...FYN in early embryonic growth cones combined with its early peak of expression suggests an important role for FYN in ear...

Identification of protein-tyrosine kinase genes preferentially expressed in e...

Iwase(T),Tanaka(M),Suzuki(M),Naito(Y),Sugi... Biochem Biophys Res Commun 1993-08-31

...fyn, respectively. We report here that the expression levels of two families of receptor type tyrosine kinase genes, elk...

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