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Intracellular signalling via the AKT axis and downstream effectors is active ...

Golfinopoulos(V),Pentheroudakis(G),Goussia... Ann Oncol 2013-03-29

...RPS6 showed frequent expression. At univariate analysis, high IHC expression of pAKT and pRPS6 displayed statistically s...

Concurrent resistance and aerobic exercise stimulates both myofibrillar and m...

Donges(Cheyne E),Burd(Nicholas A),Duffield... J Appl Physiol (1985) 2013-01-17

...rpS6 (Ser(235/236)) increased only in RE (10.4) (P < 0.05). CE and AE both resulted in increased peroxisome proliferator...

Suppressed RNA-polymerase 1 pathway is associated with benign multiple sclero...

Achiron(Anat),Feldman(Anna),Magalashvili(D... PLoS One 2013-03-28

...RPS6. In accordance POL-1 transcript and release factor PTRF that terminates POL-1 transcription, was over-expressed (p ...

Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density ...

Hulmi(Juha J),Oliveira(Bernardo M),Silvenn... Am J Physiol Endocrinol Met... 2013-02-27

...rpS6 and S6K1, r = 0.8). Concurrently, increased REDD1 and eIF2Bε protein contents and phosphorylation of 4E-BP1 and AMP...

Activation of placental mTOR signaling and amino acid transporters in obese w...

Jansson(Nina),Rosario(Fredrick J),Gaccioli... J Clin Endocrinol Metab 2013-03-07

...RPS6, and AMPK) in the placental insulin/IGF-I, AMPK, and mTOR signaling pathways. The activity and protein expression o...

Pharmacological targeting of mammalian target of rapamycin inhibits ovarian g...

Rico(Charlène),Laguë(Marie-Noëlle),Lefèvre... Carcinogenesis 2013-01-17

...RPS6KB1 and RPS6 were decreased (P < 0.05) by everolimus, but RPS6KB1, RPS6, eIF4B and PPARG expressions were not affect...

Inhibition of calcineurin in the prefrontal cortex induced depressive-like be...

Yu(Jing-Jie),Zhang(Yong),Wang(Ying),Wen(Zi... Psychopharmacology (Berl) 2013-06-10

...rps6).,Chronic microinjection of CsA or FK506 into mPFC increased depressive-like behaviors and decreased mTOR activity,...

Psk1, an AGC kinase family member in fission yeast, is directly phosphorylate...

Nakashima(Akio),Otsubo(Yoko),Yamashita(Aki... J Cell Sci 2013-08-28

...Rps6 constitutes a nutrient-dependent signaling pathway in fission yeast.

TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal prote...

Du(Wei),Hálová(Lenka),Kirkham(Sara),Atkin(... Biol Open 2012-12-06

...Rps6) and regulates its phosphorylation status. It has previously been shown that Gad8 is phosphorylated by TORC2. Consi...

Alcohol-induced decrease in muscle protein synthesis associated with increase...

Lang(Charles H),Pruznak(Anne M),Nystrom(Ge... Nutr Metab (Lond) 2012-10-02

...rpS6 and eIF4G was decreased.,These data indicate that muscle protein synthesis is equally sensitive to the inhibitory e...

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