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FATP5 modulates biological activity and lipid metabolism in prostate cancer thr…

Liu(S),He(Y),Gu(Z) Front Oncol 2024-00-00

...TEAD4, and this transcriptional activation requires the involvement of YAP1. FATP5 is highly expressed in prostate cance...

Structural and ligand-binding analysis of the YAP-binding domain of transcripti…

Li(Y),Liu(S),Ng(EY),Li(R),Poulsen(A),Hill(J)… Biochem J 2018-00-26

...TEAD4 (mTEAD4) that interact with these compounds. Flufenamic acid (FA) was used as a positive control for validation of...

[YAP induces chromosomal instability in liver cancer patients].

Weiler(S) Pathologe 2018-12-00

...TEAD4 and FOXM1, YAP induces the expression of genes which are responsible for the development of chromosomal instabilit...

Characterization of the acute heat stress response in gilts: III. Genome-wide a…

Kim(KS),Seibert(JT),Edea(Z),Graves(KL),Kim(E… J Anim Sci 2018-06-04

...TEAD4), ΔTR (LIMS2, TTR, and TEAD4), and ΔTS (ERBB4, FKBP1B, NFATC2, and ATP9A) have reported roles in the cellular stre...

Isolation and characterization of trophoblast-derived stem-like cells from peri…

Suasnavas(EA),Heywood(S),Ward(A),Cox(L),O'Gr… Anim Reprod Sci 2015-03-00

...TEAD4, CYP17A1, HSD17B1, FGFR2, PLET, HAND1) as well as some genes known to mediate pluripotency (POU5F1, KLF4, CMYC). P...

Stapled peptide inhibitors target VGLL4/TEAD4 interactions to accelerate cutane…

Chen(S),Gai(C),Wang(G),Dong(P),Zhuo(X),Zhang… Eur J Med Chem 2026-02-15

...TEAD4-VGLL4 interactions can initiate tissue repair and regeneration. Peptides have been created to modulate PPIs with v...

Decoy Extracellular Vesicles Overcome Triple-Negative Breast Cancer Heterogenei…

Chen(C),Shen(M),Wan(X),Sheng(L),Hao(N),Li(M)… Adv Sci (Weinh) 2025-10-00

...TEAD4-siRNA (siTEAD4) and a mitochondria-targeting metal-organic framework (T/MOF) to overcome tumor heterogeneity. Extr...

Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of…

Meinhardt(G),Haider(S),Kunihs(V),Saleh(L),Po… Proc Natl Acad Sci U S A 2020-00-16

...TEAD4 complexes to promoters of proliferation-associated genes such as CCNA and CDK6 Moreover, repressive YAP-TEAD4 comp...

YAP-mediated macrophage polarization is involved in progression of atherosclero…

Zhang(X),Sun(X),Qin(Q),Hou(Y),Jia(M),Su(X),C… Eur J Pharmacol 2025-12-05

...TEAD4 in RAW264.7 cells. Notably, AAV-mediated macrophage-specific knockdown of YAP substantially mitigated atherosclero...

YAP-induced Ccl2 expression is associated with a switch in hepatic macrophage i…

Thomann(S),Weiler(SME),Wei(T),Sticht(C),De L… Liver Int 2021-08-30

...TEAD4)-dependent manner. Ccl2 expression was associated with a loss of Kupffer cells (KCs) and an increase in immature m...

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