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Disruption of the csk gene, encoding a negative regulator of Src family tyros...

Imamoto(A),Soriano(P) Cell 1993-07-22

...Fyn kinase. Phosphorylation at the carboxy-terminal tyrosine of Src was reduced but not eliminated and was accompanied b...

c-Yes tyrosine kinase activity in human colon carcinoma.

Park(J),Meisler(A I),Cartwright(C A) Oncogene 1993-10-18

...fyn (Fyn), p59hck (Hck), p56lyn (Lyn) and p55c-fgr (Fgr) from colonic cells. Yes activity, similar to that of Src, was 1...

Induction of tumor formation and cell transformation by polyoma middle T anti...

Thomas(J E),Aguzzi(A),Soriano(P),Wagner(E ... Oncogene 1993-09-28

...Fyn immunoprecipitates displayed fourfold lower levels of middle T phosphorylation than that detected in the Src and Yes...

Substrate specificity for normal but not mutationally activated variants of s...

Sartor(O),Robbins(K C) J Biol Chem 1993-11-24

...fyn, fgr, and src translational products by transfection of appropriate cDNAs into mouse fibroblasts. Because the same p...

Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyro...

Dosil(M),Wang(S),Lemischka(I R) Mol Cell Biol 1993-10-26

...Fyn, and Src are components of the Flk2/Flt3 signal transduction pathway. In addition, we demonstrate that phospholipase...

SH2 domains recognize specific phosphopeptide sequences.

Songyang(Z),Shoelson(S E),Chaudhuri(M),Gis... Cell 1993-04-21

...Fyn, Lck, Fgr, Abl, Crk, and Nck) preferred sequences with the general motif pTyr-hydrophilic-hydrophilic-Ile/Pro while ...

Mutation of a cysteine residue in polyomavirus middle T antigen abolishes int...

Glenn(G M),Eckhart(W) J Virol 1993-04-08

...fyn and c-yes), and phosphatidylinositol-3 kinase. We made a single point mutation in MT, changing a conserved cysteine ...

T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domai...

da Silva(A J),Janssen(O),Rudd(C E) J Exp Med 1993-12-28

...fyn-SH3 domain) of p59fyn(T). Further, based on the results of in vitro kinase assays, p120/130 appears to be preferenti...

Tyrosine-phosphorylation of tubulin during monocytic differentiation of HL-60...

Katagiri(K),Katagiri(T),Kajiyama(K),Yamamo... J Immunol 1993-02-05

...Fyn and Lyn, which were abundantly induced during monocytic differentiation of HL-60 cells, were demonstrated to be asso...

Activation of Src family kinases by colony stimulating factor-1, and their as...

Courtneidge(S A),Dhand(R),Pilat(D),Twamley... EMBO J 1993-04-23

...Fyn, and the isolated SH2 domain of Fyn was capable of binding the CSF-1R in vitro. Analysis of mutant CSF-1Rs revealed ...

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