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Multiple signal transduction pathways activated through the T cell receptor f...

Siegel(J N),Egerton(M),Phillips(A F),Samel... Semin Immunol 1992-04-23

...fyn as an important candidate for the TCR tyrosine kinase. The protein tyrosine phosphatase CD45 also plays a critical e...

Biochemical and cytological changes associated with expression of deregulated...

Unger(T F),Steele(R E) Mol Cell Biol 1992-12-29

...fyn, a src-family member, resulted in a phenotype similar to that seen with deregulated src. However, in the fyn-injecte...

Association of Fyn with the activated platelet-derived growth factor receptor...

Twamley(G M),Kypta(R M),Hall(B),Courtneidg... Oncogene 1992-10-26

...fyn (Fyn) and pp62c-yes (Yes)] are ubiquitously expressed, and are thus likely to have general roles in growth control. ...

High-efficiency expression/cloning of epidermal growth factor-receptor-bindin...

Margolis(B),Silvennoinen(O),Comoglio(F),Ro... Proc Natl Acad Sci U S A 1992-11-10

...fyn and the mouse homologue of phospholipase C-gamma 1, whereas two genes encoded proteins similar to v-crk and NCK. We ...

pp59fyn mutant mice display differential signaling in thymocytes and peripher...

Stein(P L),Lee(H M),Rich(S),Soriano(P) Cell 1992-10-07

...fyn, a nonreceptor protein tyrosine kinase related to pp60src, by homologous recombination in embryonic stem cells. fyn-...

Protein tyrosine kinases belonging to the src family.

Toyoshima(K),Yamanashi(Y),Inoue(K),Semba(K... Ciba Found Symp 1992-11-19

...fyn, lyn and fgr genes in lymphocytes and monocytes are discussed.

Membrane immunoglobulin and its accomplices: new lessons from an old receptor...

Cambier(J C),Campbell(K S) FASEB J 1992-11-19

...fyn, lyn, blk, and lck and other SH2-containing molecules such as phosphatidylinositol 3-kinase. Available evidence indi...

Differential regulation of T cell antigen responsiveness by isoforms of the s...

Davidson(D),Chow(L M),Fournel(M),Veillette(A) J Exp Med 1992-06-23

...fyn isoform (fynB) is highly expressed in brain, the alternative product (fynT) is principally found in T lymphocytes. T...

Comparison of src-family cDNAs reveals distinct mechanisms underlying focus f...

Sartor(O),McLellan(C A),Chiueh(T) J Biol Chem 1992-11-18

...fyn. These studies support the previously published concept that overexpression of the normal fyn protein contributes to...

Comparison of tyrosine kinase activation by mitogenic and nonmitogenic anti-I...

Brunswick(M),Burkhardt(A),Finkelman(F),Bol... J Immunol 1992-10-20

...Fyn, and Lyn. These results suggest that the extent of tyrosine kinase activation is proportional to mIg cross-linking, ...

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