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Suppression of dedifferentiation and hypertrophy in canine chondrocytes throu...

Gurusinghe(Saliya),Young(Peter),Michelsen(... Biotechnol Lett 2016-02-25

...col2a1 without an increase in the hypertrophy marker collagen X in 3D pellet cultures.

Systematic study of cell isolation from bovine nucleus pulposus: Improving ce...

Lee(Juliana T Y),Cheung(Kenneth M C),Leung... J Orthop Res 2016-02-22

...COL2A1, CDH2, KRT18, and KRT19 expression compared to muscle cells for different cell isolation conditions tested. Diges...

Identification of a Novel Mutation in the COL2A1 Gene in a Chinese Family wit...

Huang(Xiangjun),Deng(Xiong),Xu(Hongbo),Wu(... PLoS One 2016-03-04

...COL2A1) was identified. The mutation may impair protein stability, and lead to dysfunction of type II collagen. Family-b...

Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor ...

Kamimura(Masayuki),Mori(Yu),Sugahara-Tobin... PLoS One 2016-04-12

...Col2a1 and Col10a1 in DAP12-/- mice increased and subsequently became higher than those in B6 mice. There was a decrease...

Regenerative and immunogenic characteristics of cultured nucleus pulposus cel...

Stich(Stefan),Stolk(Meaghan),Girod(Pierre ... PLoS One 2016-04-15

...COL2A1 in 2D- and 3D-culture with degeneration- and culture-dependent differences. In a 5,6-carboxyfluorescein diacetate...

Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiatio...

Park(Na-Rae),Lim(Kyung-Eun),Han(Min-Su),Ch... J Cell Physiol 2016-01-19

...Col2a1 promoter. Cbfb(Δch/Δch) mice died soon after birth and exhibited delayed endochondral bone formation, shorter app...

Identification of a novel mutation of the COL2A1 gene in a Chinese family wit...

Li(Hongzhuo),Ma(Liang),Wang(Baozhu),Cui(Yu... Eur Spine J 2016-02-16

To identify potential disease-causing mutation in the COL2A1 gene in a Chinese family with autosomal dominant spondyloep...

Decreased Zn(2+) Influx Underlies the Protective Role of Hypoxia in Rat Nucle...

Yin(Xiao-Fan),Jiang(Li-Bo),Ma(Yi-Qun),Xu(J... Biol Trace Elem Res 2016-07-26

...COL2A1, MMP-13, and ADAMTS-5 mRNA expression. ZIP8, a main Zn(2+) transporter in chondrocytes, was assayed by immunochem...

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increa...

Long(D L),Ulici(V),Chubinskaya(S),Loeser(R F) Osteoarthritis Cartilage 2016-06-13

...COL2A1 expression.,HB-EGF is a new factor identified in OA cartilage that promotes chondrocyte catabolic activity while ...

A pilot study of gene testing of genetic bone dysplasia using targeted next-g...

Zhang(Huiwen),Yang(Rui),Wang(Yu),Ye(Jun),H... J Hum Genet 2016-10-05

...COL2A1 gene and PHEX gene were found in nine patients, respectively (9/44=20%), followed by COMP gene in 8 (18%), TRPV4 ...

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