Comuzzie(A G),Hixson(J E),Almasy(L),Mitche... Nat Genet 1997-04-04

...GCKR) and pro-opiomelanocortin (POMC). Our results show strong evidence of linkage of this region of chromosome 2 with s...

Hayward(B E),Fantes(J A),Warner(J P),Intod... Mamm Genome 1997-01-21

...GCKR as a further candidate gene for type 2 diabetes. The inhibition of GCK by GCKR is relieved by the binding of fructo...

Warner(J P),Leek(J P),Intody(S),Markham(A ... Mamm Genome 1996-03-25

...GCKR). Given the role of GCK in MODY, GCKR is itself a candidate type 2 diabetes susceptibility gene. Here we describe t...

Petit(Jean-Michel),Masson(David),Guiu(Bori... Acta Diabetol 0000-00-00

It has recently been shown that an allele in the glucokinase regulatory protein (GCKR) gene was associated with increase...

Dongiovanni(Paola),Valenti(Luca) Metabolism 0000-00-00

...GCKR enhance de novo hepatic lipogenesis in response to glucose and liver inflammation. Furthermore, the low-frequency E...

Tin(A),Balakrishnan(P),Beaty(T H),Boerwink... Diabet Med 0000-00-00

...GCKR (rs1260326, T allele β=0.08; P=1.8×10(-47) ) and PPP1R3B/LOC157273 (rs9987289, A allele β=0.06; P=1.6×10(-9) ). The...

Agius(Loranne) Proc Nutr Soc 0000-00-00

...GCKR, G6PC, SLC37A4) and triose phosphate pool (PKLR); (iii) ChREBP knock-down models have elevated hepatic hexose phosp...

Klimentidis(Yann C),Arora(Amit) Circ Cardiovasc Genet 0000-00-00

...GCKR, CILP2, and IRS1, whereas PIGV-NROB2 and LRPAP1 display an opposite trend of interaction. In the pooled data set, w...

Grove(Jane I),Austin(Mark),Tibble(Jeremy),... Ann Hepatol 0000-00-00

...GCKR, TRIB1, LYPLAL1, PPP1R3B, COL13A1, and EFCAB4B, previously implicated in contributing to non-alcoholic steatohepati...

Hu(Yao),Li(Huaixing),Lu(Ling),Manichaikul(... Hum Mol Genet 0000-00-00

...GCKR. Different effect sizes in FADS1 and independent association signals in ELOVL2 were observed. These results provide...