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di Blasio(Laura),Gagliardi(Paolo Armando),... J Cell Sci 2015-12-21

...PDK1 binds and phosphorylates integrin αvβ3. Downregulation of PDK1 increases FA size and slows down their disassembly. ...

Swift(Joshua M),Smith(Joan T),Kiang(Julian... Radiat Res 2015-08-24

...PDK1, an enzyme responsible for PDH phosphorylation) after combined injury were also prevented by ciprofloxacin treatmen...

Wheeler(Douglas B),Zoncu(Roberto),Root(Dav... Science 2015-11-03

...PDK1 and mTORC2 and copurifies with PI3K in immunoprecipitation assays. Two somatic RAB35 mutations found in human tumor...

Kim(Seung-Chang),Jang(Hong-Chul),Lee(Sung-... J Anim Sci Technol 2015-08-20

...PDK1, protein kinase B; Akt, forkhead box protein O1; FOXO1 and cGMP-inhibited 3', 5'-cyclic phosphodiesterase; PDE3) lo...

Lee-Rivera(Irene),López(Edith),Parrales(Al... Exp Eye Res 2015-12-03

...PDK1/Akt activity, that of Ccnd1 is mediated by PDK1-independent PKCζ signaling. Additionally, CREB activation may contr...

Guo(Chenxu),Wu(Yingchun),Zhu(Yuanzhang),Wa... Evid Based Complement Alter... 2015-06-19

...PDK1 and Akt phosphorylation in Hep3B cells. Moreover, YSC-ZDC increased Bax expression and inhibited Bcl-2 expression. ...

Mao(Dan),Sun(Xiaodong) Invest Ophthalmol Vis Sci 2015-10-27

...PDK1), phospho-Bcl-2 death promotor (p-BAD), cytosolic cytochrome c (Cyt c), and cleaved Caspase-3 were detected by West...

Hu(Tianyuan),Li(Cong),Zhang(Yingchi),Wang(... Biochem Biophys Res Commun 2015-06-05

...PDK1 in the regulation of LSCs in AML is still not clear. Using a PDK1 conditional deletion MLL-AF9 murine AML model, we...

Lucero-Acuña(Armando),Jeffery(Justin J),Ab... Int J Nanomedicine 2015-09-09

...PDK1, which has shown a good therapeutic effect against a BxPC3 pancreatic cancer model that has K-ras, but has a poor t...

Wang(Xiaoqiu),Johnson(Greg A),Burghardt(Ro... Biol Reprod 2015-10-23

...PDK1-Akt/PKB-TSC2-MTORC1 cell signaling cascade. Collectively, results suggest that arginine and SPP1 in histotroph act ...