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Ageing is associated with reduction of mechanically-induced activation of Sma...

Madej(W),van Caam(A),Davidson(E N Blaney),... Osteoarthritis Cartilage 2016-09-26

...Col2a1) and fibronectin (Fn1) expression to a far lesser extent than in young cartilage. Additionally, in aged cartilage...

Radiation-induced alterations of osteogenic and chondrogenic differentiation ...

Cruet-Hennequart(Séverine),Drougard(Carole... PLoS One 2016-03-15

...COL2A1, ACAN and SOX9 mRNA amounts associated with a RUNX2 increase. Together with collagens I and II proteins decrease,...

Role of c-Myb in chondrogenesis.

Oralová(V),Matalová(E),Janečková(E),Drobná... Bone 2016-02-26

...Col2a1 and activity of a Col2-LUC reporter were increased in the cells overexpressing c-myb while late chondrogenic mark...

Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human plur...

Umeda(Katsutsugu),Oda(Hirotsugu),Yan(Qing)... Stem Cell Reports 2016-01-06

...COL2A1) of neural crest origin (SOX8/9, NGFR, NES). Ectomesenchyme is a source of many craniofacial bone and cartilage s...

All-trans-retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud me...

Zhang(Tao-Gen),Li(Xue-Dong),Yu(Guo-Yong),X... Mol Med Rep 2016-01-05

...Col2a1), were downregulated by ATRA in a dose-dependent manner; the mRNA levels of p53 and p21 were dose-dependently upr...

Suppression of dedifferentiation and hypertrophy in canine chondrocytes throu...

Gurusinghe(Saliya),Young(Peter),Michelsen(... Biotechnol Lett 2016-02-25

...col2a1 without an increase in the hypertrophy marker collagen X in 3D pellet cultures.

A pilot study of gene testing of genetic bone dysplasia using targeted next-g...

Zhang(Huiwen),Yang(Rui),Wang(Yu),Ye(Jun),H... J Hum Genet 2016-10-05

...COL2A1 gene and PHEX gene were found in nine patients, respectively (9/44=20%), followed by COMP gene in 8 (18%), TRPV4 ...

Mutation Update for COL2A1 Gene Variants Associated with Type II Collagenopat...

Barat-Houari(Mouna),Sarrabay(Guillaume),Ga... Hum Mutat 2016-10-13

...COL2A1-associated Czech dysplasia. LOVD-COL2A1 provides support and potential collaborative material for scientific and ...

Osteogenic Profile of Mesenchymal Cell Populations Contributing to Alveolar B...

Minaříková(Monika),Oralová(Veronika),Vesel... Cells Tissues Organs 2016-09-14

...Col2a1, Sox9, Smad2 and Vegfb. To confirm these changes in gene expression, immunofluorescence analyses of Mmp9 and Sox9...

[CHONDROGENESIS-SPECIFIC MICRORNA EXPRESSION PATTERN ANALYSIS IN CHONDROGENIC...

Zhang(Ziji),Kang(Yan),Zhang(Zhiqi),Yang(Zi... Zhongguo Xiu Fu Chong Jian ... 2016-03-02

...Col2a1, aggrecan, Coll0a1, and chondroitin sulfate in induced hADSCs were significantly higher than those in non-induced...

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