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Zhou(Xiangyu),Cordon-Barris(Lluis),Zurashv... Cell Cycle 2015-09-10

...PDK1 to phosphorylate and activate PKB. In the PDK1 K465E knock-in mice expressing a mutant form of PDK1 incapable of ph...

Seong(Hyun-A),Manoharan(Ravi),Ha(Hyunjung) Cell Cycle 2015-07-20

...PDK1 signaling pathways. Moreover, knockdown of endogenous MPK38 using an inducible MPK38 shRNA system and in vivo activ...

Xu(Jia),Wu(Chun-lian),Huang(Jie) Zhongguo Zhong Yao Za Zhi 2015-09-08

...PDK1 in Akt signal pathway in a dose-dependent manner. Therefore, the study implies that Celastrol could inhibit the met...

Yu(Wan-Guo),He(Hao),Yao(Jing-Yun),Zhu(Yi-X... Biomol Ther (Seoul) 2015-11-04

...PDK1), and protein kinase C alpha (PKCα). All these data demonstrated that DMC had anti-inflammatory effects through red...

Byelinska(I V),Lynchak(O V),Tsyvinska(S M)... Fiziol Zh 2015-11-24

...PDK1, Src(h), Syk(h), YES, ZAP70 et al. with antineoplastic activity, on blood cells parameters of rats after chronic ex...

Takahashi(Kenji),Yan(Irene K),Haga(Hiroaki... J Cell Sci 2015-04-09

...PDK1 and HIF-1α protein expression and increased expression of the linc-RoR target microRNA-145 (miR-145). Linc-RoR was ...

Ye(Xian-wei),Yu(Hong),Jin(Yan-kun),Jing(Xi... Clin Respir J 2015-10-06

...PDK1. Finally, the role of PDK1 on proliferation of A549 cells was evaluated by transefection of PDK1 small interfering ...

Zabkiewicz(Joanna),Pearn(Lorna),Hills(Robe... Haematologica 2015-04-13

...PDK1 promoted the survival of myeloid cell lines. Analysis of PDK1 target kinases revealed that PDK1 overexpression was ...

Caohuy(Hung),Yang(Qingfeng),Eudy(Yvonne),H... J Biol Chem 2015-04-14

...PDK1 and permit PDK1 to autophosphorylate at Ser(241). Then PDK1[Ser(P)(241)] phosphorylates SGK1[Ser(P)(422)] at Thr(25...

Parker(Robert),Clifton-Bligh(Roderick),Mol... Mol Cancer Ther 2015-04-20

...PDK1 phosphorylation. These findings highlight a role for CK2 blockade in potentiating the antiproliferative effects of ...