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Rab3A is required for brain-derived neurotrophic factor-induced synaptic plas...

Thakker-Varia(S),Alder(J),Crozier(R A),Plu... J Neurosci 2001-09-20

...Rab3A effector molecules were induced by BDNF at either the gene or protein levels. The functional role of Rab3A in BDNF...

A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effect...

Kajio(H),Olszewski(S),Rosner(P J),Donelan(... Diabetes 2001-09-20

...Rab3A. The calmodulin-Rab3A interaction was pH- and Ca2+-dependent, and it was preferential for GTP-bound Rab3A. However...

Evidence for targeted vesicular glutamate exocytosis in osteoblasts.

Bhangu(P S),Genever(P G),Spencer(G J),Grew... Bone 2001-10-25

...Rab3A are also identified by northern blot analysis. Finally, we demonstrate that osteoblastic cells actively release gl...

Developmental regulation and specific brain distribution of phosphorabphilin.

Foletti(D L),Scheller(R H) J Neurosci 2001-08-16

...Rab3A, binds Ca(2+) and phospholipids, and interacts with cytoskeletal elements, yet its function remains controversial....

Physiological modulation of rabphilin phosphorylation.

Foletti(D L),Blitzer(J T),Scheller(R H) J Neurosci 2001-08-16

...Rab3a, a small GTPase that recruits rabphilin to synaptic vesicles. The rapid phosphorylation and dephosphorylation duri...

Synaptotagmin VI participates in the acrosome reaction of human spermatozoa.

Michaut(M),De Blas(G),Tomes(C N),Yunes(R),... Dev Biol 2001-08-09

...Rab3A triggers acrosomal exocytosis at very low calcium concentration. Rab3A-promoted exocytosis was inhibited by the cy...

Subcellular distribution and function of Rab3A-D in pancreatic acinar AR42J c...

Piiper(A),Leser(J),Lutz(M P),Beil(M),Zeuze... Biochem Biophys Res Commun 2001-11-01

...Rab3A-D). In the present study, we examined the subcellular distribution of endogenously expressed Rab3 proteins and the...

Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially relate...

Wang(X),Hu(B),Zimmermann(B),Kilimann(M W) J Biol Chem 2001-10-18

...Rab3A (K(d) on the order of magnitude of 10-100 microm) to this region of rabphilin-3 alone (amino acids 40-88), whereas...

Rab3A and Rab3D control the total granule number and the fraction of granules...

Martelli(A M),Baldini(G),Tabellini(G),Koti... Traffic 2001-05-03

...Rab3A and Rab3D can coexist on the same granule before and after docking. Using electron microscopy of transfected PC12 ...

Structural plasticity of an invariant hydrophobic triad in the switch regions...

Merithew(E),Hatherly(S),Dumas(J J),Lawe(D ... J Biol Chem 2001-06-14

...Rab3A and the Rab3A-specific effector Rabphilin3A (Ostermeier, C., and Brunger, A. T. (1999) Cell 96, 363-374). Here, we...

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