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Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to ma...

Andres-Mateos(Eva),Brinkmeier(Heinrich),Bu... EMBO Mol Med 2013-06-06

...SGK1) regulates muscle mass maintenance via downregulation of proteolysis and autophagy as well as increased protein syn...

Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO...

Amato(R),Scumaci(D),D'Antona(L),Iuliano(R)... Oncogene 2013-11-14

...Sgk1 regulates cell proliferation, we adopted a proteomic approach to identify up- or downregulated proteins after Sgk1-...

Functional expression of TRPV4 channels in human collecting duct cells: impli...

Hills(Claire E),Bland(Rosemary),Squires(Pa... Exp Diabetes Res 2013-01-30

...SGK1 expression. Touch-evoked changes were negated following TRPV4 knockdown.,Our data confirm expression of Ca²⁺-depend...

Mineralocorticoid receptors/epithelial Na(+) channels in the choroid plexus a...

Nakano(Masatsugu),Hirooka(Yoshitaka),Matsu... Hypertens Res 2013-08-26

...Sgk1) expression levels in the CP were measured and found to be greater in SHRSP than in Wistar-Kyoto (WKY) rats. CSF [N...

Aging-like skin changes in metabolic syndrome model mice are mediated by mine...

Nagase(Takashi),Akase(Tomoko),Sanada(Hirom... Aging Cell 2013-09-30

...Sgk1 was significantly upregulated in the aging-like skin in the UV-irradiated MetS mice. Furthermore, topical applicati...

Regulation of ion channels by the serum- and glucocorticoid-inducible kinase ...

Lang(Florian),Shumilina(Ekaterina) FASEB J 2013-03-07

...SGK1 on channel activity is modest, and the channels do not require SGK1 for basic function. SGK1-dependent ion channel ...

Disease-causing R1185C mutation of WNK4 disrupts a regulatory mechanism invol...

Na(Tao),Wu(Guojin),Zhang(Wei),Dong(Wen-Ji)... Am J Physiol Renal Physiol 2013-04-03

...SGK1) phosphorylation sites S1190 and S1217. In addition, we identified a novel SGK1 phosphorylation site (S1201) in WNK...

Low SGK1 expression in human adrenocortical tumors is associated with ACTH-in...

Ronchi(Cristina L),Sbiera(Silviu),Leich(El... J Clin Endocrinol Metab 2013-02-12

...SGK1, SGK3, and CTNNB1 (coding for β-catenin) and protein expression levels of SGK1, nuclear β-catenin, and phosphorylat...

A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in ...

Raikwar(Nandita S),Liu(Kang Z),Thomas(Chri... Am J Physiol Renal Physiol 2013-04-02

...Sgk1 isoform, Sgk1_i3. Sgk1_i3 contains a polybasic motif, KKR, in its NH(2) terminus that regulates ubiquitination and ...

Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of a...

Schmid(Evi),Gu(Shuchen),Yang(Wenting),Münz... Am J Physiol Cell Physiol 2013-03-06

...SGK1. Moreover, FcεRI-dependent degranulation is decreased in SGK1-deficient (sgk1(-/-)) MCs. The present study addresse...

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