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Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the c…

Clark(Patsy),Dziarmaga(Alison),Eccles(Michae… J Am Soc Nephrol 2004-09-20

...Pax2(1Neu) mutant mice and rescue the genetic UB branching defect. E17.5 kidneys from Pax2(1Neu) mutant mice had smaller...

Association of PAX2 with cell apoptosis in unilateral ureteral obstruction rats.

Zhou(Tian-Biao),Qin(Yuan-Han),Lei(Feng-Ying)… Ren Fail 2012-05-29

...PAX2) plays a major role in the development of the kidney. This study was performed to investigate whether PAX2 was asso...

Less expression of prohibitin is associated with increased paired box 2 (PAX2) …

Zhou(Tian-Biao),Zeng(Zhi-Yu),Qin(Yuan-Han),Z… Int J Mol Sci 2015-08-31

Prohibitin (PHB) and paired box 2 (PAX2) are associated with the development of renal interstitial fibrosis (RIF). This ...

[Clinicopathologic study and immunohistochemistry comparison of Pax2, p53 and K…

Shen(Xu-xia),Yu(Lin),Bi(Rui),Yang(Wen-tao) Zhonghua Bing Li Xue Za Zhi 2012-04-05

...Pax2 (65.8% vs 13.0%, P < 0.05). (3) Pax2 positive cases had a significantly better overall survival and 5-year survival...

Motoneuron-derived neurotrophin-3 is a survival factor for PAX2-expressing spin…

Béchade(Catherine),Mallecourt(Catherine),Sed… J Neurosci 2002-11-25

...PAX2-IR interneurons. Addition of NT-3 to 192 IgG-saporin-treated explants rescued ventral PAX2-IR interneurons. Depleti...

Renal hypoplasia: lessons from Pax2.

Dziarmaga(Alison),Quinlan(Jacklyn),Goodyer(P… Pediatr Nephrol 2006-09-29

The functions of Pax2 during renal development are many. It organizes caudal descent of the nephric duct, emergence of t...

Dishevelled-3 activates p65 to upregulate p120-catenin transcription via a p38-…

Zhao(Huanyu),Zhao(Yue),Jiang(Guiyang),Zhang(… Mol Carcinog 2015-09-08

...PAX2 promoter to increase the expression of PAX2 and then PAX2 binds to p120ctn promoter so as to upregulate p120ctn gen...

PAX2 Gene Mutation in Pediatric Renal Disorders-A Narrative Review.

Muntean(C),Chirtes(C),Baczoni(B),Banescu(C) Int J Mol Sci 2023-08-13

The PAX2 gene is a transcription factor that is essential for the development of the urinary system among other transcri...

Pax2a, but not pax2b, influences cell survival and periocular mesenchyme locali…

Lusk(S),Kwan(KM) Dev Dyn 2022-00-00

...pax2a and pax2a; pax2b mutants. Apoptosis is not up-regulated within the optic fissure in pax2 mutants, yet cell death i...

Distinct regulators control the expression of the mid-hindbrain organizer signa…

Ye(W),Bouchard(M),Stone(D),Liu(X),Vella(F),L… Nat Neurosci 2002-01-11

...Pax2, further refines the expression domain and level of FGF8 at the MHB through opposing effects on Pax2 activity. Our ...

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