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Innovative computational approaches shed light on genetic mechanisms underlying…

Liu(W),Sun(Q),Huang(L),Bhattacharya(A),Wang(… J Neurodev Disord 2022-00-03

...TEAD4 at rs11829294, p value = 2.40e-8) and syntaxin 18 (STX18 at rs79453226, p value = 1.91e-8). Integrative analysis w...

c-Abl controls early embryonic morphogenesis through YAP/p73-dependent regulati…

Yildirim(E),Onel(T),Yaba(A) Cell Commun Signal 2026-01-15

...TEAD4, CDX2, NANOG, E-cadherin, and PARD6. These changes collectively affect blastomere morphology, cell-cell adhesion, ...

Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mo…

Rayon(T),Menchero(S),Nieto(A),Xenopoulos(P),… Dev Cell 2014-08-25

...TEAD4. Notch activity is restricted to outer cells and is able to influence positional allocation of blastomeres, mediat...

IGF2BP2 promotes the progression of colorectal cancer through a YAP-dependent m…

Cui(J),Tian(J),Wang(W),He(T),Li(X),Gu(C),Wan… Cancer Sci 2021-10-00

...TEAD4 enrichment in ErbB2 promoter region. Therefore, IGF2BP2 promoted the expression of ErbB2 to enhance the proliferat...

A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylati…

Liu(Y),Zhu(L),Ming(Y),Wu(Z),Zhang(L),Chen(Q)… J Transl Med 2023-00-17

...TEAD4 on TRIM59 was confirmed by qPCR, western blot, luciferase reporter assay, ChIP and DNA pull-down. In order to unco...

Evidence of Oocyte Polarity in Bovine; Implications for Intracytoplasmic Sperm …

Hosseini(SM),Moulavi(F),TanhaieVash(N),Shams… Cell J 2017-10-00

...Tead4 were significantly higher in HNS oocyte fragment compared t0 FS. The relative abundances of Ctnb, Carm1, Rex1, Sox...

YAP1 Depletion Enhances TAZ and its Complexation with TEAD4 and AP-1 Heterodime…

Wu(J),Athavale(D),Balch(C),Zhao(J),Zou(G),Fa… bioRxiv 2025-11-14

...TEAD4 and AP1 (c-JUN and FOSB) heterodimer was observed following YAP1 knockdown or pharmacological ASO inhibition. Dual...

In Vitro Model of Human Trophoblast in Early Placentation.

Bačenková(D),Trebuňová(M),Čížková(D),Hudák(R… Biomedicines 2022-04-15

...TEAD4, Eomes and GATA3, leads to the formation of cytotrophoblast and syncytiotrophoblast populations. The molecular mec...

Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects…

Sabir(DK) Med Oncol 2025-01-08

...TEAD4, MET, LPAR1, and ADCY9 in colorectal cancer, highlighting their involvement in the Hippo and Rap1 signaling pathwa...

Bisphenol A promotes colorectal cancer malignancy through CXCL8 upregulation as…

Ao(W),Li(H),Zhang(Y),Wu(Z),Yang(H),Chen(Z) Chem Biol Interact 2026-08-27

...TEAD4 was identified as a potential upstream transcriptional regulator of CXCL8, while increased CXCL8 expression was ac...

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