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Identification of new microRNA genes and aberrant microRNA profiles in childhoo…

Schotte(D),Chau(J C K),Sylvester(G),Liu(G),C… Leukemia 2009-03-02

...PBX1, hyperdiploid and B-other cases than in 20 MLL-rearranged and 15 T-ALL cases (0.0001

Immunohistochemical demonstration of angiogenesis-associated homeobox proteins …

Kodama(A),Sakai(H),Murakami(M),Murai(A),Mori… J Comp Pathol 2009-09-22

...Pbx1 and Meis1. Quiescent ECs in granulation tissue did not express HoxD3 and Pbx1. There were significantly more neopla...

Gfi1 integrates progenitor versus granulocytic transcriptional programming.

Horman(Shane R),Velu(Chinavenmeni S),Chaubey… Blood 2009-06-16

...Pbx1, and Meis1 during normal myelopoiesis. Gfi1-/- progenitors exhibit elevated levels of HoxA9, Pbx1 and Meis1, exagge...

The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essentia…

Scheele(Jürgen S),Kolanczyk(Mateusz),Gantert… Leuk Lymphoma 2009-08-27

...PBX1. The goal of this work was to elucidate the mechanisms by which E2a-Pbx1 can lead to deregulated target gene expres...

Treating childhood acute lymphoblastic leukemia without cranial irradiation.

Pui(Ching-Hon),Campana(Dario),Pei(Deqing),Bo… N Engl J Med 2009-07-06

...PBX1), any CNS involvement at diagnosis, and T-cell immunophenotype. Common adverse effects included allergic reactions ...

KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells.

Chan(Ken Kwok-Keung),Zhang(Jingyao),Chia(Na-… Stem Cells 2009-12-11

...PBX1 or mutation of KLF4/PBX1 binding motifs significantly downregulated NANOG promoter activity. We also showed that sp...

Transcriptional activation by MEIS1A in response to protein kinase A signaling …

Goh(Siew-Lee),Looi(Yvonne),Shen(Hui),Fang(Ju… J Biol Chem 2009-09-01

...PBX1, and TORC2 on the MEIS1 target genes Hoxb2 and Meis1. The MEIS1 interaction domain on TORC1 was mapped to the N-ter...

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD …

Wang(Gang G),Song(Jikui),Wang(Zhanxin),Dorma… Nature 2009-08-05

...Pbx1), and enforced their active gene transcription in murine haematopoietic stem/progenitor cells. Mechanistically, NUP...

Molecular and chromosomal mutations among children with B-lineage lymphoblastic…

Mesquita(D R),Córdoba(J C),Magalhães(I Q),Có… Genet Mol Res 2009-08-05

...PBX1, BCR/ABL p190, and MLL/AF4. The frequencies of these transcripts were 21.21, 9.68, 3.03, and 0%, respectively. All ...

[Detection of fusion genes resulting from chromosome abnormalities in childhood…

He(Jun),Chen(Zi-xing),Xue(Yong-quan),Li(Jian… Zhonghua Yi Xue Yi Chuan Xue … 2009-03-19

...PBX1, E2A/HLF, TLS/ERG, MLL/AF4, MLL/AF9, MLL/AF10, MLL/AFX-MLL/AF6-MLL/ELL, MLL/AF6-MLL/ELL, dupMLL (one case for each)...

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