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Establishment of human induced trophoblast stem-like cells from term villous cy…

Bai(T),Peng(CY),Aneas(I),Sakabe(N),Requena(D… Stem Cell Res 2021-00-00

...TEAD4 and ELF5, and are multipotent, validated by their differentiation into both extravillous trophoblasts (EVT) and sy...

The TEAD4-YAP/TAZ protein-protein interaction: expected similarities and unexpe…

Hau(JC),Erdmann(D),Mesrouze(Y),Furet(P),Font… Chembiochem 2013-07-08

The Hippo pathway controls cell homeostasis, and its deregulation can lead to human diseases. In this pathway, the YAP a...

Identification of Small-molecule YAP-TEAD inhibitors by High-throughput docking…

Li(L),Li(R),Wang(Y) Bioorg Chem 2022-00-00

...TEAD4 inhibitor through docking-based virtual screening. L06 inhibits TEAD autopalmitoylation, interrupts YAP-TEAD inter...

A retinoic acid:YAP1 signaling axis controls atrial lineage commitment.

Abraham(E),Kostina(A),Volmert(B),Roule(T),Hu… Cell Rep 2025-05-27

...TEAD4 are integrated with the atrial transcription factor enhancer network and that YAP1 activates RA enhancers in CPCs....

TEAD-YAP Interaction Inhibitors and MDM2 Binders from DNA-Encoded Indole-Focuse…

Kunig(VBK),Potowski(M),Akbarzadeh(M),Klika Š… Angew Chem Int Ed Engl 2020-00-09

...TEAD4 yielded MDM2 binders and a novel class of TEAD-YAP interaction inhibitors that perturbed the expression of a gene ...

Lnc-uc.147 Is Associated with Disease Stage of Liver, Gastric, and Renal Cancer.

Rodrigues(AC),Zambalde(EP),Bellan(DL),Trinda… Biomolecules 2023-00-31

...TEAD4 and lnc-uc.147 in liver and breast cancer cells.

Macrophage-derived SPP1 promotes subretinal fibrosis by YAP1 phase separation i…

Lin(R),Cai(Z),Zheng(T),Wu(Y),Xu(Z),Luo(Y),Li… Metabolism 2026-08-00

...TEAD4, thereby promoting EMT-like changes in RPE. Under accumulation of acidic metabolites, SPP1-overexpressing Mφs prom...

Identification of crucial genes associated with esophageal squamous cell carcin…

Wang(X),Li(G),Luo(Q),Gan(C) Oncol Lett 2018-06-00

...TEAD4)] were enriched in the primary metabolic process and intracellular membrane-bounded organelle. Additionally, 308 u...

Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical pept…

Tokareva(OS),Li(K),Travaline(TL),Thomson(TM)… Nat Commun 2023-00-01

...TEAD4), and a transcriptional coactivator (β-catenin).

A Fragment Screen Identifies Acrylamide Covalent Inhibitors of the TEAD•YAP Pro…

Bum-Erdene(K),Ghozayel(MK),Zhang(MJ),Gonzale… bioRxiv 2026-03-20

...TEAD4 binding to YAP. Synthesis of a focused set of derivatives and time- and concentration-dependent studies with four ...

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