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H3K18la- driven neutrophil secretory autophagy promotes pulmonary endothelial d…

Li(Y),Li(R),Zhu(D),Tian(R),Chen(Y),Wang(X),L… Autophagy 2026-06-12

...CST3: cystatin C; CXCL8/IL-8: C-X-C motif chemokine ligand 8; DAPI: 4',6-diamidino-2-phenylindole; DEG: differentially e...

Transcriptomic Identification of Renin-Angiotensin System-Related Candidate Bio…

Bai(J),Wang(Y),Yang(X),Du(L),Shi(J),Li(X),Ba… J Vis Exp 2026-06-22

...CST3, FURIN, and TBXAS1 were further validated at the protein level. CST3 and FURIN modulation altered Ang II-induced en...

Frailty phenotype, genetic risk and long-term incident systemic lupus erythemat…

Deng(P),Yan(S),Lu(J) Clin Med (Lond) 2026-07-00

...CST3 and TNFSF8 as the candidate risk-related biomarkers associated with future incident SLE. Frailty is associated with...

A large-scale plasma proteomic study reveals the preclinical evolution and pote…

Wang(C),Yan(C),Ren(Q),Lu(S),Wang(N),Guo(Y),S… Cardiovasc Pathol None

...CST3 exhibited progressive abnormalities approximately 8 to 13 years prior to diagnosis. The model constructed using onl...

Multi-Omics discovery and clinical validation of IGFBP2, B2M, and CST3 as a ser…

Wu(J),Yin(T),Zhang(Z),Yin(R),Metwally(E),Li(… Gene 2026-02-05

...CST3/IGFBP2 and rivipansel to B2M. Through a multi-omics approach, we identified IGFBP2/B2M/CST3 as a non-invasive bioma...

GZMK+CD8+ T cells target a specific acinar cell type in Sjögren's disease.

Pranzatelli(TJF),Perez(P),Ku(A),Matuck(B),Hu… Ann Rheum Dis 2026-05-00

...CST3⁺WFDC2⁻ seromucous acinar population that is selectively lost in Sjögren's disease. Expression and organizational ch...

Necrotising enterocolitis biomarkers: a systematic review.

Faizan(MA),Khalid(I),Yeo(A),Fadel(MM),Mcmaho… Front Pediatr None

...CST3), Pigment Epithelium Derived Factor (PEDF), and Retinol Binding Protein 4 (RET4) (96% sensitivity, 90% specificity)...

Integrative proteomics and metabolomics reveal important pathways and potential…

Dan-Zeng(ZG),Bai-Ma(YJ),Huang(J),Suo-Lang(WJ… Sci Rep 2025-07-11

...CST3 (downregulated). Our integrated multi-omics analysis reveals a complex molecular network underlying HAPH pathogenes...

Two Japanese families with adult-onset leukoencephalopathy caused by pathogenic…

Orimo(K),Matsukawa(T),Shiomi(K),Goto(R),Mits… J Neurol Sci 2025-11-15

CST3 (NM_000099.4) encodes cystatin C, whose C-terminal truncating variants in this gene have recently been reported to ...

Life's Essential 8, phenotypic age, and cardiovascular age in prediabetes: pred…

Chen(C),Li(C),Zhu(Q),Yang(Y),Jia(S),Zhang(X)… Eur J Med Res 2025-10-06

...CST3, EFEMP1, FES, IGFBP2, IGFBP6, LPA, PCSK9, and TIMP1 mediated these effects. Over a median follow-up of 13.4 years, ...

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