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Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at dia...

Garg(Manoj),Nagata(Yasunobu),Kanojia(Deepi... Blood 2016-03-18

...FAT4, and IDH3B. Mutations in 9 genes were observed in the relapse-specific phase. DNMT3A mutations are the most stable ...

Inhibitory mechanism of FAT4 gene expression in response to actin dynamics du...

Ito(Takao),Taniguchi(Hiroaki),Fukagai(Kous... PLoS One 2016-04-29

...FAT4 acts as a tumor suppressor in humans, and reduced FAT4 gene expression has been reported in breast and lung cancers...

A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Ca...

Cheng(Feixiong),Liu(Chuang),Lin(Chen-Ching... PLoS Comput Biol 2016-03-30

...FAT4, STAG2, and SYNE1). The tumor genomes harboring the nonsynonymous somatic mutations in these genes had a higher mut...

Gene mutations in gastric cancer: a review of recent next-generation sequenci...

Lin(Y),Wu(Z),Guo(W),Li(J) Tumour Biol 2016-02-02

...FAT4, CTNNA1), cytoskeleton and cell motility (RHOA), Wnt pathway (CTNNB1, APC, RNF43), and RTK pathway (RTKs, RAS famil...

Target-enriched next-generation sequencing reveals differences between primar...

Crobach(Stijn),Ruano(Dina),van Eijk(Ronald... J Mol Diagn 2016-04-25

...FAT4 versus APC, TP53, KRAS, and FAT4 mutations were the most common in the primary ovarian tumors and ovarian colorecta...

Inferring the progression of multifocal liver cancer from spatial and tempora...

Shi(Jie-Yi),Xing(Qingfeng),Duan(Meng),Wang... Oncotarget 2016-11-11

...FAT4 expression and FAT4 mutational status significantly correlated with patient prognosis. Together, our findings sugge...

FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-c...

Cai(Jian),Feng(Dan),Hu(Liang),Chen(Haiyang... Br J Cancer 2016-05-10

...FAT4 in gastric cancer and examined the underlying molecular mechanisms.,The expression of FAT4 was evaluated by immunoh...

Age-related mutations and chronic myelomonocytic leukemia.

Mason(C C),Khorashad(J S),Tantravahi(S K),... Leukemia 2016-09-15

...FAT4, ARIH1, DNAH2 and CSMD1. Most CMML patients (71%) had mutations in ⩾2 ARCH genes and 52% had ⩾7 mutations overall. ...

Sall1 in renal stromal progenitors non-cell autonomously restricts the excess...

Ohmori(Tomoko),Tanigawa(Shunsuke),Kaku(Yus... Sci Rep 2016-09-23

...Fat4, which restricts nephron progenitor expansion, was reduced mildly. Furthermore, the Sall1 protein binds to many str...

Fat4 suppression induces Yap translocation accounting for the promoted prolif...

Ma(Liangang),Cui(Jianxin),Xi(Hongqing),Bia... Cancer Biol Ther 2016-10-31

...Fat4 due to frequent gene mutation was detected in a variety of tumors including gastric cancer, where Fat4 was recogniz...

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