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Downregulation of KRTAP2-3 Suppresses Proliferation and Tumor Formation of Or...

Miao(Q),Huang(Z),Takahashi(K),Ibi(H),Miyaz... Cancer Sci 2026-07-21

...FOSL1), poor prognostic factors in HNSCC. Knockdown of either FGF-5 or FOSL1 significantly reduced OSCC cell proliferati...

FOSL1 Orchestrates Epigenetic Reprogramming of Anaplastic Thyroid Cancer and ...

Huo(Y),Huang(Y),Yu(X),Han(L),Zhang(L),Huan... Cancer Res 2026-05-04

...FOSL1 as a driver of epigenetic remodeling and immune escape, highlighting the potential of targeting FOSL1 in anaplasti...

The Histone Methyltransferase KMT2D Is a Critical Mediator of Lineage Plastic...

Kittane(S),Ladewig(E),Li(T),Love(JR),Blaws... Cancer Res 2026-03-02

...FOSL1, which acts as a master regulator of this subtype. Single-cell transcriptomics and chromatin assays underscored th...

Targeting pre-existing club-like cells in prostate cancer potentiates androge...

Baurès(M),Vieira Aleixo(AS),Pacreau(E),Kos... EMBO Mol Med 2026-03-00

...FOSL1/AP-1. We demonstrate that cells exhibiting Ptenpc-/- LSCmed characteristics are prevalent in aggressive double-neg...

LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis.

Shi(J),Wang(X),Tang(Y),Meng(S),Zhang(Z),Lu... Gut 2026-07-08

...FOSL1-dependent epigenetic-transcriptional reprogramming. In human PDAC, LY6D+ cells harbour stemness and Epithelial-Mes...

Inhibition of FOS-Like Antigen 1 Reduces Chemoresistance to Temozolomide Thro...

Sim(J),Park(J),Heo(J),Kim(YJ),Kim(D),Jeon(... MedComm (2020) 2026-02-00

...FOSL1-mediated stemness. Mechanistically, in vitro experiments demonstrated that FOSL1 induces GBM stemness through IL-6...

Bifidobacterium Infantis Promotes FOSL1-Mediated Transcriptional Repression o...

Tang(J),Li(Q),Li(K),Hang(D),Gu(D),Feng(L),... Inflammation 2026-01-23

...FOSL1) knockdown. AIP progression, mitigated by FOSL1 knockdown after B. infantis colonization in mice, was exacerbated ...

FOSL1 promotes homologous recombination repair and camptothecin resistance vi...

Hao(C),Chen(L),Liao(F),Chen(L),Yao(Y),Song(Q) Transl Oncol 2026-04-00

...FOSL1 expression and nuclear accumulation, whereas FOSL1 depletion markedly enhanced CPT-induced cytotoxicity. Mechanist...

Comprehensive analysis of disulfidptosis-related genes identifies clinically ...

Xing(R),Chen(C),Yang(Y),Zhou(H),Hu(M) Discov Oncol 2026-02-16

...FOSL1, and COX6B2—were identified to construct the prognostic model. The high-risk group exhibited significantly poorer ...

3C suppresses PINK1-mediated mitophagy and contributes to coxsackievirus B3 r...

Liu(T),Wan(A),Xu(Y),Lu(H),Xie(Y),Wu(H),Wan... Virulence 2026-12-00

...FOSL1 as a novel negative regulator of PINK1 transcription through direct promoter binding. Collectively, these findings...

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