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FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phos…

Wei(L),Wei(W),Wang(Q),Li(D),Hu(B),Fan(F),Liu… J Transl Med 2026-03-05

...GOT1 and MDH1 were upregulated, suggesting alterations in the malate-aspartate shuttle. Meanwhile, glycolytic activity i...

2-Oxocarboxylic acid metabolic pathway fuels mitochondrial ATP synthesis to pow…

Ye(L),Zhang(Q),Yang(J),Cheng(D) Insect Mol Biol 2026-08-00

...GOT1]) within this pathway showed continuous expression increases, peaking at the oviposition stage, and were specifical...

Lipotoxic hepatocyte-derived UBQLN1-enriched small extracellular vesicles activ…

Yang(F),Chen(Y),Wang(Y),Zheng(G),Abouelnazar… Autophagy 2026-08-00

...GOT1/AST: glutamic-oxaloacetic transaminase; GPT/ALT: glutamic-pyruvic transaminase; hiPSCs: human induced pluripotent s...

Chronic thermal stress affects growth, liver morphology and molecular responses…

Adzijovski(M),Schultz(AG),Bergfeld(J),Afonso… J Fish Biol 2026-08-00

...got1) and growth (igf1, ghra) were consistently upregulated in T4 fish at Days 30 and 60, while expression in recovery f...

Oncolytic virus hijacks GOT1 and pyrimidinosomes to fuel pyrimidine synthesis f…

Tang(N),Gong(Y),Zhao(C),Niu(Y),Tan(L),Song(C… Tumour Virus Res 2026-06-00

...GOT1) as a key metabolic enzyme required for efficient viral replication through its dual role in de novo pyrimidine syn...

GOT1 inhibits hepatocellular carcinoma progression by regulating SLC25A5-depend…

Zong(W),Cheng(C),Zhang(Y),Lu(Y),Lian(Z),Luo(… Oncogene 2026-06-00

...GOT1) in HCC progression and evaluated its therapeutic potential. GOT1 expression was markedly downregulated in HCC tiss...

Expression of sulfate pathway genes in human neurodevelopment.

Vijayakumar(P),Summers(KM),Dawson(PA) J Neurogenet None

...GOT1, IDS, HS3ST2, HS3ST4, HS6ST3, SLC26A8, STS, SULT1A1, SULT4A1, UST) were expressed in the hippocampus and clustered ...

Liver-originated selective autophagy of BTD by alectinib underlies concurrent h…

Huang(X),Zhang(S),Mu(Y),Zhou(Y),Chen(X),Xia(… Autophagy 2026-09-00

...GOT1/AST: glutamic-oxaloacetic transaminase 1; GPT/ALT: glutamic--pyruvic transaminase; GSEA: gene set enrichment analys...

Induced pluripotent stem cells from a transgenic minipig model of Huntington's …

Rysankova(I),Sekac(D),Hansikova(H),Kepkova(K… Dis Model Mech 2026-06-01

...GOT1), implying early metabolic alteration in TgHD iPSCs. Moreover, upregulated FANCD2/FANCI-associated nuclease 1 (FAN1...

Role of glutamine metabolism reprogramming in ferroptosis of lens epithelial ce…

Jiang(C),Xu(Z),Lu(Y),Du(L) Free Radic Biol Med 2026-07-00

...GOT1). Genetic or pharmacological inhibition of SLC1A5, GLS2 or GOT1 was effective in preventing glutamine degradation, ...

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