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Boldine Mitigates Chronic Unpredictable Stress-Induced Depression by Suppress...

Akotkar(L),Aswar(U) ACS Pharmacol Transl Sci 2026-05-08

...Htr1a gene expression, suggesting serotonergic modulation. Histopathological evaluation confirmed BDN neuroprotective ef...

Meta-analysis of Cannabis Use Identifies Shared Genetic Loci with Sleep and C...

Valliere(J),Strausz(S),Tchio(C),Risse-Adam... medRxiv 2026-04-16

...HTR1A, RAI1, SLC39A8, and NCAM1. Moreover, tissue-specific analyses revealed that the genetic architecture of cannabis u...

Association of Cognition-Related Genetic Polymorphisms with Elite Athlete Sta...

Akkuş(E),Eyipınar(CD),Buzdagli(Y) Genes (Basel) 2026-04-09

...HTR1A rs6295. Pooled analyses were performed using a fixed-effect model, and odds ratios (ORs) with 95% confidence inter...

Carbon dioxide stunning of pigs induces the expression of fear-associated gen...

Gelhausen(J),Paul(NF),Knöll(J),Wilk(I),Mör... Sci Rep 2026-05-06

...HTR1A and HTR2A, which encode serotonin receptors, were downregulated in the animals stunned with CO2. Both receptors ha...

Pharmacogenetics of venlafaxine response in older adults with depression and ...

Kronenbuerger(M),Magarbeh(L),Kloiber(S),Ta... Pharmacogenomics None

...HTR1A) variant rs6295 emerged as the most consistent nominal genetic signal. Previously reported pharmacogenetic signal ...

Effects of SSRIs on the spatial transcriptome of dorsal raphe serotonin neurons.

Henningson(C),Mlost(J),Pollak Dorocic(I) Mol Psychiatry 2026-05-15

...Htr1a expression increased following acute treatment but decreased after chronic administration, supporting previous fin...

Distribution of Metabotropic Serotonin Receptors in GABAergic and Glutamaterg...

Galindo(KL),Nazir(ZA),Silveira(MA) J Comp Neurol 2026-02-00

...Htr1a and Htr1b, inhibitory, Gi/o G protein receptors), 5-HT2A, 5-HT2B, and 5-HT2C (Htr2a, Htr2b, and Htr2c excitatory, ...

An isoflavone-enriched diet alleviates Parkinson's disease in mice by inhibit...

Yang(L),Ma(Y),Wang(H),Xie(L),Yu(Y) Front Immunol None

...HTR1A), which in turn triggers downstream PI3K-AKT signaling to suppress ferroptosis-a key pathogenic process in PD. Pha...

Screening natural raw materials and product development for improving insomni...

Yue(L),Jiao(Q),Li(J),Lu(Y),Yi(M),He(C),Jia(Y) Medicine (Baltimore) 2026-01-23

...HTR1A, 7 raw materials related to target GABRB2, and 582 raw materials related to target GABRA1. Then based on the scree...

An Efficient Pharmacogenomic Assay for Psychotropic Drugs by Multiplex Fluore...

Zheng(J),Zou(Q),Wang(C),Yang(Q),Ren(J),Cao... Drug Des Devel Ther None

...HTR1A, HTR2A, and MC4R genes. Utilizing multiplex fluorescence melting curve analysis (mFMCA), a four-channel multiplex ...

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